Journal article
Conjunctival stromal tumor: Report of 2 new cases and review of the literature
International Journal of Surgical Pathology
2020
Abstract
Conjunctival stromal tumor (COST) is an emerging entity with only a limited number of cases reported in the literature. In this report, we describe 2 additional cases, review the accumulative clinical and histopathological features and expand on the immunophenotypic property of this entity. COST appears to have a sporadic presentation, affecting both sexes and patients of variable ethnicity and age group and predominantly occurring on the bulbar conjunctiva as a slow-growing asymptomatic or slightly tender mass-like lesion. Histopathologically, COST is characterized by singly dispersed spindle to round cells, often with some degree of degenerative nuclear atypia, within a myxomatous to collagenous stroma. Lesional cells are characteristically positive for CD34 and vimentin, negative for S100, SOX10 and STAT6 and show a normal pattern of staining with RB1 by immunohistochemistry. The reported cases to date have shown an indolent biological behavior, reliably treated by a complete surgical excision.
Details
- Title
- Conjunctival stromal tumor: Report of 2 new cases and review of the literature
- Authors/Creators
- J. Lam (Author/Creator) - The University of Western AustraliaA. Ang (Author/Creator) - The University of Western AustraliaT. Vermeulen (Author/Creator) - Pathwest Laboratory MedicineN.M. Ardakani (Author/Creator) - The University of Western Australia
- Publication Details
- International Journal of Surgical Pathology
- Publisher
- SAGE Publications
- Identifiers
- 991005542555707891
- Copyright
- © 2020 by SAGE Publications
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
20 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.118 Soft Tissue, Bone & Nerve Cancers
- 1.118.1488 Cardiac Tumors
- Web Of Science research areas
- Pathology
- Surgery
- ESI research areas
- Clinical Medicine