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Consanguineous marriage and its clinical consequences in migrants to Australia
Journal article   Peer reviewed

Consanguineous marriage and its clinical consequences in migrants to Australia

J. Nelson, M.T. Smith and A.H. Bittles
Clinical Genetics, Vol.52(3), pp.142-146
2008
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Abstract

Marriage between close biological relatives is strongly favoured in many countries in Asia and Africa. Although substantial numbers of migrants from these regions are now living in Australia, little information is available either on the prevalence of consanguineous unions among migrants or on their clinical outcome. Data are presented on a range of generally rare autosomal recessive genetic disorders diagnosed in the children of parents of Eastern Mediterranean origin who attended Westmead Hospital, Sydney for genetic counselling during the period 1990 to 1994. The effects of parental consanguinity are assessed both in terms of the specific recessive disorders detected, and the perceived role of consanguineous marriage in the communities investigated.

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