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Construction of a map-based reference genome sequence for barley, Hordeum vulgare L
Journal article   Open access   Peer reviewed

Construction of a map-based reference genome sequence for barley, Hordeum vulgare L

S. Beier, A. Himmelbach, C. Colmsee, X-Q Zhang, R.A. Barrero, Q. Zhang, L. Li, M. Bayer, D. Bolser, S. Taudien, …
Scientific Data, Vol.4, Article number: 170044
2017
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Abstract

Barley (Hordeum vulgare L.) is a cereal grass mainly used as animal fodder and raw material for the malting industry. The map-based reference genome sequence of barley cv. ‘Morex’ was constructed by the International Barley Genome Sequencing Consortium (IBSC) using hierarchical shotgun sequencing. Here, we report the experimental and computational procedures to (i) sequence and assemble more than 80,000 bacterial artificial chromosome (BAC) clones along the minimum tiling path of a genome-wide physical map, (ii) find and validate overlaps between adjacent BACs, (iii) construct 4,265 non-redundant sequence scaffolds representing clusters of overlapping BACs, and (iv) order and orient these BAC clusters along the seven barley chromosomes using positional information provided by dense genetic maps, an optical map and chromosome conformation capture sequencing (Hi-C). Integrative access to these sequence and mapping resources is provided by the barley genome explorer (BARLEX).

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#13 Climate Action
#15 Life on Land

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.4 Crop Science
3.4.96 QTL
Web Of Science research areas
Biotechnology & Applied Microbiology
ESI research areas
Molecular Biology & Genetics
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