Convenient Asymmetric Synthesis of (1R,3R)-(+)- and (1S,3S)-(-)-1,3-Diphenylpropane-1,3-diols

G. Roos; A.R. Donovan

doi:10.1055/s-1996-5703

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Convenient Asymmetric Synthesis of (1R,3R)-(+)- and (1S,3S)-(-)-1,3-Diphenylpropane-1,3-diols

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Convenient Asymmetric Synthesis of (1R,3R)-(+)- and (1S,3S)-(-)-1,3-Diphenylpropane-1,3-diols

G. Roos and A.R. Donovan

Synlett, Vol.1996(12), pp.1189-1190

1996

DOI: https://doi.org/10.1055/s-1996-5703

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Abstract

Kinetic resolution via a Sharpless epoxidation serves as the key step to provide the useful C2 chiral auxiliaries (R,R)- and (S,S)-1,3-diphenylpropane-1,3-diols, in good yield and high enantiomeric purity from the commercially available 1,3-diphenylprop-1-en-3-one. Sharpless epoxidation - Kinetic resolution - Asymmetric synthesis - C2 symmetric 1,3-diols - 1,3-Diphenylpropan-1,3-diols

Details

Title: Convenient Asymmetric Synthesis of (1R,3R)-(+)- and (1S,3S)-(-)-1,3-Diphenylpropane-1,3-diols
Authors/Creators: G. Roos (Author/Creator)
A.R. Donovan (Author/Creator)
Publication Details: Synlett, Vol.1996(12), pp.1189-1190
Publisher: Thieme
Identifiers: 991005543851007891
Murdoch Affiliation: School of Chemical and Mathematical Science
Language: English
Resource Type: Journal article

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