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Convenient synthetic route to antimicrobial benzo[c]pyranquinones
Journal article   Open access   Peer reviewed

Convenient synthetic route to antimicrobial benzo[c]pyranquinones

R.G.F. Giles, I.R. Green, V.I. Hugo, F.J. Oosthuisen and N. van Eeden
South African Journal of Chemistry, Vol.48(1-2), pp.15-22
1995
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Abstract

A genera) synthetic strategy has been developed for the synthesis of racemic 3,4-dihydro-3-methyl-1 Hbenzo[ c]pyran-5,8-dione 25, trans-0 fl,3fl)-5,8-dihydroxy-1,3-dimethyl-4-oxo-lH-benzo[cjpyran 39, rel- {1fl,3R,4H)-3,4-dihydro-1,3-dimethyl-4-hydroxy-1H-benzo[c]pyran-5,8-dione 41 and the re/-(4S)-diastereoisomer 42.

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