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Cross-reactivity between vancomycin, teicoplanin and telavancin in HLA-A*32:01 positive vancomycin DRESS patients sharing an HLA-Class II haplotype
Journal article   Open access   Peer reviewed

Cross-reactivity between vancomycin, teicoplanin and telavancin in HLA-A*32:01 positive vancomycin DRESS patients sharing an HLA-Class II haplotype

N. Nakkam, A. Gibson, E. Mouhtouris, K. Konvinse, N. Holmes, K.Y. Chua, P. Deshpande, D. Li, D.A. Ostrov, J. Trubiano, …
Journal of Allergy and Clinical Immunology, Vol.147(1), pp.P403-P405
2020
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Abstract

All fifteen patients with HLA-A*32:01 restricted vancomycin-induced DRESS, showed negative ex vivo responses to dalbavancin however two showed cross-reactivity to teicoplanin and telavancin. Adjunctive diagnostic testing should be considered to detect potential cross-reactivity amongst glycopeptides.

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Citation topics
1 Clinical & Life Sciences
1.265 Dermatology - Skin Allergies
1.265.1140 Drug Hypersensitivity
Web Of Science research areas
Allergy
Immunology
ESI research areas
Immunology
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