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Cryptosporidium GP60 genotypes from humans and domesticated animals in Australia, North America and Europe
Journal article   Peer reviewed

Cryptosporidium GP60 genotypes from humans and domesticated animals in Australia, North America and Europe

E. O'Brien, L. McInnes and U. Ryan
Experimental Parasitology, Vol.118(1), pp.118-121
2008
DOI: https://doi.org/10.1016/j.exppara.2007.05.012
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Abstract

To investigate the molecular epidemiology of Cryptosporidium species in children in Australia, fecal specimens from 50 Australian children with gastrointestinal symptoms and seven isolates from Australian neonatal dairy calves were genotyped and sub-genotyped at the 18S rDNA and GP60 loci, respectively, and compared with human and animal isolates collected from Europe, the US and Canada (n = 35). Results revealed that the majority of the Australian human isolates were infected with C. hominis (41/50), while the remainder were infected with C. parvum. All the Australian cattle as well as cattle from US, Canada, UK and Switzerland were infected with C. parvum. Subtyping of 92 Cryptosporidium isolates at the GP60 locus identified seven subtype families of which six were identified in Australian isolates; four C. hominis subtypes and two C. parvum subtypes. Results suggest that although transmission is largely anthroponotic in Australia, cattle may be a source of sporadic human infections.

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Source: InCites

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Citation topics
1 Clinical & Life Sciences
1.246 Diarrheal Diseases
1.246.985 Cryptosporidium
Web Of Science research areas
Parasitology
ESI research areas
Microbiology
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