Cytochrome P450 Gene, CYP6CX3, is involved in the resistance to Cyantraniliprole in Bemisia tabaci

Z. Zhang; Z. Wen; K. Li; W. Xu; N. Liang; X. Yu; C. Li; D. Chu; L. Guo

doi:10.1021/acs.jafc.2c04699

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Cytochrome P450 Gene, CYP6CX3, is involved in the resistance to Cyantraniliprole in Bemisia tabaci

Journal article

Peer reviewed

Cytochrome P450 Gene, CYP6CX3, is involved in the resistance to Cyantraniliprole in Bemisia tabaci

Z. Zhang, Z. Wen, K. Li, W. Xu, N. Liang, X. Yu, C. Li, D. Chu and L. Guo

Journal of Agricultural and Food Chemistry, Vol.70(39), pp.12398-12407

2022

DOI: https://doi.org/10.1021/acs.jafc.2c04699

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Abstract

Bemisia tabaci is an important agricultural sucking pest, and it develops serious resistance to various insecticides. Although cytochrome P450 was involved in the resistance to cyantraniliprole, limited studies have been conducted on B. tabaci. In the present study, piperonyl butoxide significantly increased the toxicity of cyantraniliprole. P450 activities in two resistant populations were 1.97- and 2.17-fold higher than that in the susceptible population. Among 79 P450 genes, CYP6CX3 expressions in two resistant populations were 3.08- and 3.67-fold higher than that in the susceptible population. When CYP6CX3 was knocked down, the toxicity of cyantraniliprole increased significantly. The LC50 value of cyantraniliprole to the Drosophila melanogaster line overexpressing B. tabaciCYP6CX3 increased 7.34-fold. The content of cyantraniliprole was decreased by 25.74 ± 4.27% after mixing with CYP6CX3 and CPR for 2 h. These results suggested that the overexpression of CYP6CX3 was likely involved in the resistance to cyantraniliprole in B. tabaci.

Details

Title: Cytochrome P450 Gene, CYP6CX3, is involved in the resistance to Cyantraniliprole in Bemisia tabaci
Authors/Creators: Z. Zhang (Author/Creator) - Qingdao Agricultural University
Z. Wen (Author/Creator) - Qingdao Agricultural University
K. Li (Author/Creator) - Qingdao Agricultural University
W. Xu (Author/Creator) - Murdoch University
N. Liang (Author/Creator) - Qingdao Agricultural University
X. Yu (Author/Creator) - Qingdao Agricultural University
C. Li (Author/Creator) - Qingdao Agricultural University
D. Chu (Author/Creator) - Qingdao Agricultural University
L. Guo (Author/Creator) - Qingdao Agricultural University
Publication Details: Journal of Agricultural and Food Chemistry, Vol.70(39), pp.12398-12407
Publisher: American Chemical Society
Identifiers: 991005540082007891
Copyright: © 2022 American Chemical Society
Murdoch Affiliation: Food Futures Institute
Language: English
Resource Type: Journal article

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Citation topics: 3 Agriculture, Environment & Ecology; 3.32 Entomology; 3.32.827 Insecticide Resistance
Web Of Science research areas: Agriculture, Multidisciplinary; Chemistry, Applied; Food Science & Technology
ESI research areas: Agricultural Sciences