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Cytoplasmic inheritance and its implications for animal biotechnology
Journal article   Peer reviewed

Cytoplasmic inheritance and its implications for animal biotechnology

J.M. Cummins
Theriogenology, Vol.55(6), pp.1381-1399
2001
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Abstract

At fertilization, the mammalian sperm transmits the haploid paternal genome. However, it also carries a variety of other factors into the oocyte that have the potential to affect embryo development. These include mRNAs left over from spermatogenesis, mitochondria with their own DNA, cytoskeletal and contractile elements, remnants of the sperm plasma membrane and, in many species, the sperm centriole. While most of these elements are eliminated, some play essential roles in early embryogenesis. In this review, I summarize the latest information on these phenomena and indicate some of the implications for animal biotechnology and, in particular, cloning.

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Citation topics
1 Clinical & Life Sciences
1.81 Reproductive Biology
1.81.339 Embryo Development
Web Of Science research areas
Reproductive Biology
Veterinary Sciences
ESI research areas
Plant & Animal Science
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