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Deep-frozen allogeneic cancellous bone grafts in 10 dogs: A case series
Journal article   Peer reviewed

Deep-frozen allogeneic cancellous bone grafts in 10 dogs: A case series

SHARON C. Kerwin, DANIEL D. Lewis, A. DERRELL Elkins, JULIAN Oliver, ROBERT Pechman, ROBERT J. Mccarthy and GISELLE Hosgood
Veterinary surgery, Vol.25(1), pp.18-28
1996
PMID: 8719083
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Abstract

Deep-frozen, aseptically collected and processed allogeneic cancellous bone was implanted in eight dogs during the surgical repair of diaphyseal long bone fractures and in two dogs during arthrodeses. A combined allogeneic and autogeneic cancellous bone graft was used in two fractures with a segmental bone loss of more than 5 cm. Bone union occurred in five fractures and in both arthrodeses. Failure of fixation occurred in two dogs with nonunion fractures and in a third dog with an open, infected fracture. Biopsies from the fracture sites were obtained from these dogs following failure of their fracture fixation. The cancellous bone graft appeared to be in the process of normal incorporation in each case. Failure of fixation was attributed to technical or case management errors or both, in each of the three fractures that failed to achieve bony union. Frozen allogeneic cancellous bone grafts were effectively incorporated when used in the primary repair of fractures and arthrodeses. Combined autogenous and allogeneic cancellous bone grafts may be particularly useful in the repair of fractures with large segmental diaphyseal bone defects. The use of allogeneic cancellous bone grafts in nonunion fractures requires further investigation before it can be recommended.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.34 Orthopedics
1.34.800 Fracture Management
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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