Journal article
Detection of Helicobacter pylori antigen in faeces by enzyme immunoassay
Pathology, Vol.33(4), pp.496-497
2001
Abstract
The detection of Helicobacter pylori antigen directly in faecal specimens may offer an alternative non-invasive method for determining the presence of H. pylori infection. This study compared the performance of the Premier Platinum HpSA enzyme immunoassay (HpSA) with histology and CLOtest, a rapid urease test. Of 134 patients undergoing upper gastrointestinal endoscopy, 37 (28%) were H. pylori-positive by histology and CLOtest. Using the HpSA test, H. pylori was detected in 35 H. pylori-positive patients (95% sensitivity) and one H. pylori-negative patient (99% specificity). The positive and negative predictive values for HpSA were 97 and 98%, respectively. HpSA is a rapid, easily performed, non-invasive method for detecting H. pylori.
Details
- Title
- Detection of Helicobacter pylori antigen in faeces by enzyme immunoassay
- Authors/Creators
- G.W. Coombs (Author/Creator)N.M. Foster (Author/Creator)J.W. Pearman (Author/Creator)G.M. Forbes (Author/Creator)
- Publication Details
- Pathology, Vol.33(4), pp.496-497
- Publisher
- Taylor & Francis
- Identifiers
- 991005540282707891
- Copyright
- © 2001 Royal College of Pathologists of Australasia.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.95 Gastrointestinal & Esophageal Diseases
- 1.95.387 Helicobacter Pylori
- Web Of Science research areas
- Pathology
- ESI research areas
- Clinical Medicine