Journal article
Differences in antigen expression within and between 10 isolates of Giardia duodenalis
Acta Tropica, Vol.54(2), pp.117-124
1993
Abstract
In this study indirect immunofluorescence was performed on both live and fixed trophozoites to determine the level of variability in surface antigen expression between 14 Giardia duodenalis isolates, using a monoclonal antibody raised against the Portland I isolate (ATCC No. 30888). Subsets of antigen positive cells were detected in 13 isolates ranging in number from <1% to 50% of the total population. The differences in antigen expression between 10 uncloned isolates did not correlate with genetic differences determined using isoenzyme analysis. Examination of four clones of the Portland I isolate showed that all of the progeny expressed surface antigen at significantly different levels to the parent.
Details
- Title
- Differences in antigen expression within and between 10 isolates of Giardia duodenalis
- Authors/Creators
- R. Hopkins (Author/Creator) - Murdoch UniversityR.C.A. Thompson (Author/Creator)R.P. Hobbs (Author/Creator) - Murdoch UniversityA.J. Lymbery (Author/Creator) - Department of Agriculture, Bunbury, AustraliaN. Villa (Author/Creator) - Cellabs, Brookvale, AustraliaT.M. Smithyman (Author/Creator) - Cellabs, Brookvale, Australia
- Publication Details
- Acta Tropica, Vol.54(2), pp.117-124
- Publisher
- Elsevier BV
- Identifiers
- 991005542795807891
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Parasitology
- Tropical Medicine
- ESI research areas
- Clinical Medicine