Journal article
Diffuse large B cell lymphoma within an anal fistula: a case report with an intriguing possible aetiology
Journal of Surgical Case Reports, Vol.2021(8), Art. rjab360
2021
Abstract
Described is a case of diffuse large B cell lymphoma that presented within a typical fistula tract, possibly secondary to oxidative stress within the fistula tract itself and consequent malignant change rather than a fistula as a consequence of necrosis in a lymphoma. If so it would be unique in the world literature. A 42-year-old fitness instructor presented with a typical appearing left lateral anal fistula. Biopsy of the fistulous tract revealed B cell lymphoma, graded 1E. Although chemotherapy cured the lymphoma, surgical treatment by ligation of the inter-sphincteric fistula tract was required to heal the fistula. At 3-year follow-up, there has been no recurrence of the lymphoma or the fistula. Neoplasia arising secondary to oxidative stress within an anal fistula is a well-established phenomenon. Early diagnosis of rare conditions associated with anal fistula can only be accomplished by routine biopsy of every fistula tract.
Details
- Title
- Diffuse large B cell lymphoma within an anal fistula: a case report with an intriguing possible aetiology
- Authors/Creators
- J. Kent (Author/Creator) - Bentley Health Service, Department of Surgery, Perth, WA 6102, Australia.D. Joske (Author/Creator) - Sir Charles Gairdner HospitalJ. Parry (Author/Creator) - Murdoch University
- Publication Details
- Journal of Surgical Case Reports, Vol.2021(8), Art. rjab360
- Publisher
- JSCR Publishing Ltd
- Identifiers
- 991005542299407891
- Copyright
- © 2021 Oxford University Press and JSCR Publishing Ltd
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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