Journal article
Disseminated T-cell lymphoma with non-epitheliotropic cutaneous involvement in a cat with erythematous patches and regenerative anemia
Journal of Veterinary Diagnostic Investigation, Vol.35(1), pp.42-46
2023
Abstract
A 14-y-old, castrated male, diabetic, domestic longhaired cat was presented for investigation of anemia. General examination revealed widespread cutaneous erythematous macules and patches. Hematology and bone marrow aspiration revealed severe regenerative anemia and marked erythroid hyperplasia, respectively. Low numbers of intermediate-to-large, atypical lymphocytes were observed in the blood smear and bone marrow aspirates. Various imaging modalities demonstrated a diffuse pulmonary bronchial pattern, multifocal mural thickening of the urinary bladder, splenomegaly, and mild tri-cavitary effusion. Skin biopsies and cytologic examination of the pleural effusion demonstrated round-cell neoplasia consistent with lymphoma. Autopsy confirmed disseminated T-cell lymphoma, mostly affecting the urinary bladder, stomach, lymph nodes, and interscapular subcutis and muscles. Angiocentrism and nerve infiltration were present. The cutaneous erythematous patches, characterized by perivascular neoplastic lymphocytic infiltrates and angiodestruction, were a manifestation of the disseminated lymphoma in this cat, similar to the lesions reported in humans affected by angioimmunoblastic T-cell lymphoma.
Details
- Title
- Disseminated T-cell lymphoma with non-epitheliotropic cutaneous involvement in a cat with erythematous patches and regenerative anemia
- Authors/Creators
- C. Robveille (Author/Creator)M.W. Kim (Author/Creator)J. Stayt (Author/Creator)C.R. Sharp (Author/Creator)K.F.A. Langner (Author/Creator)
- Publication Details
- Journal of Veterinary Diagnostic Investigation, Vol.35(1), pp.42-46
- Publisher
- SAGE Publications
- Identifiers
- 991005541821407891
- Copyright
- © 2022 by American Association of Veterinary Laboratory Diagnosticians
- Murdoch Affiliation
- School of Veterinary Medicine
- Language
- English
- Resource Type
- Journal article
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- 1.103 Blood Disorders
- 1.103.1225 Immune Thrombocytopenia
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