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Dissociation between pain and the nociceptive blink reflex during psychological arousal
Journal article   Peer reviewed

Dissociation between pain and the nociceptive blink reflex during psychological arousal

C. Koh and P.D. Drummond
Clinical Neurophysiology, Vol.117(4), pp.851-854
2006
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Abstract

To investigate the effect of psychological arousal on pain ratings and the R2 component of the electrically evoked blink reflex to a ‘pure’ noiciceptive stimulus. Pain ratings and R2 to a noiciceptive stimulus (pulse width 0.3 ms, 2 mA, delivered from a concentric electrode attached to the supraorbital region of the forehead) were investigated in 16 healthy participants before and during a serial subtraction task, and in 16 control participants who sat quietly during nociceptive stimulation. Pain ratings decreased whereas R2 amplitude increased during the serial subtraction task. Supra-spinal rather than spinal mechanisms inhibited pain perception during psychological arousal. Moreover, psychological arousal facilitated the R2 component of the blink reflex to a nociception-specific stimulus. Supra-spinal influences need to be considered during clinical evaluation of the trigeminal nociceptive blink reflex.

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Citation topics
1 Clinical & Life Sciences
1.43 Anesthesiology
1.43.135 Neuropathic Pain
Web Of Science research areas
Clinical Neurology
Neurosciences
ESI research areas
Neuroscience & Behavior
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