Dual representation of the hand in the cerebellum: Activation with voluntary and passive finger movement

G.W. Thickbroom; M.L. Byrnes; F.L. Mastaglia

doi:10.1016/S1053-8119(02)00055-1

Back

Dual representation of the hand in the cerebellum: Activation with voluntary and passive finger movement

Journal article

Peer reviewed

Dual representation of the hand in the cerebellum: Activation with voluntary and passive finger movement

G.W. Thickbroom, M.L. Byrnes and F.L. Mastaglia

NeuroImage, Vol.18(3), pp.670-674

2003

DOI: https://doi.org/10.1016/S1053-8119(02)00055-1

Files and links (1)

url

Link to Published Version *Subscription may be requiredView

Abstract

Early electrophysiological studies during sensory stimulation in the anesthetized cat and more recent functional imaging studies during voluntary movement in humans have provided evidence for two separate representations of the body in the anterior and posterior lobes of the cerebellum; however, the functional role of these body maps in motor and sensory processing is not known. The aims of the present study were to determine whether this dual representation is also present during passive movement, and to compare the pattern of activation with that obtained during voluntary movement. Functional MRI measurements were undertaken in 14 subjects who performed right index finger flexion and extension movements at ∼1 Hz, or had their finger moved passively at the same rate and through the same angle using a pneumatic device. During passive movement, dual activation was detected in the ipsilateral cerebellum, in the anterior lobe, and in the posterior lobe. A similar pattern of activation was observed during voluntary movement; however, the overall magnitude was about doubled. These data provide evidence for a dual ipsilateral representation of the hand in the rostral and caudal cerebellar cortex during passive as well as voluntary movements, with the rostral representation being the dominant one, and indicate that both of these areas are involved in kinesthetic sensory and motor processing.

Details

Title: Dual representation of the hand in the cerebellum: Activation with voluntary and passive finger movement
Authors/Creators: G.W. Thickbroom (Author/Creator) - The University of Western Australia
M.L. Byrnes (Author/Creator) - The University of Western Australia
F.L. Mastaglia (Author/Creator) - Centre for Neuromuscular and Neurological Disorders
Publication Details: NeuroImage, Vol.18(3), pp.670-674
Publisher: Elsevier
Identifiers: 991005545399407891
Copyright: © 2003 Elsevier Science (USA)
Murdoch Affiliation: Murdoch University
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Metrics

26 Record Views

50 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.5 Neuroscience; 1.5.1501 Cerebellar Function
Web Of Science research areas: Neuroimaging; Neurosciences; Radiology, Nuclear Medicine & Medical Imaging
ESI research areas: Neuroscience & Behavior