Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion

N. Keane; C. Almeida; A. Chopra; D. Cooper; E. Demaine; S. Mallal; M. John

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Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion

Journal article

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Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion

N. Keane, C. Almeida, A. Chopra, D. Cooper, E. Demaine, S. Mallal and M. John

Retrovirology, Vol.9(Suppl 2)

2012

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Abstract

Identification of the earliest CD8 T-cell responses against HIV may help select critical viral targets for inclusion in an HIV vaccine. We describe changes to the earliest detected CD8 T-cell responses and changes in genetic sequence encoding targeted epitopes in an individual who presented with Fiebig stage II, clade C acute HIV-infection, 27 days after sexual transmission.

Details

Title: Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion
Authors/Creators: N. Keane (Author/Creator)
C. Almeida (Author/Creator)
A. Chopra (Author/Creator)
D. Cooper (Author/Creator)
E. Demaine (Author/Creator)
S. Mallal (Author/Creator)
M. John (Author/Creator)
Publication Details: Retrovirology, Vol.9(Suppl 2)
Publisher: BioMed Central
Identifiers: 991005542702307891
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Language: English
Resource Type: Journal article
Note: Poster Presentation at AIDS Vaccine 2012, Boston, 9-12 September, 2012.

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