Journal article
Early detection of G+C differences in bacterial species inferred from the comparative analysis of the two completely sequenced helicobacter pylori strains
Journal of Molecular Evolution, Vol.53(4-5), pp.465-468
2001
Abstract
Identifying the G + C difference between closely related bacterial species or between different strains of the same species is one of the first steps in understanding the evolutionary mechanisms accounting for the differences observed among bacterial species. The G + C content can be one of the most important factors in the evolution of genomic structures. In this paper, we describe a new method for detecting an initial stage of differentiation of the G + C content at the third codon base position between two strains of the same bacterial species. We apply this method to the two strains of Helicobacter pylori. A group of genes is detected with large variations of G + C in the third positions—apparently genes of early response to pressures of changing G + C. We discuss our findings from the viewpoint of genomic evolution.
Details
- Title
- Early detection of G+C differences in bacterial species inferred from the comparative analysis of the two completely sequenced helicobacter pylori strains
- Authors/Creators
- M. Bellgard (Author/Creator)D. Schibeci (Author/Creator)E. Trifonov (Author/Creator)T. Gojobori (Author/Creator)
- Publication Details
- Journal of Molecular Evolution, Vol.53(4-5), pp.465-468
- Publisher
- Springer-Verlag
- Identifiers
- 991005541970307891
- Copyright
- 2001 Springer-Verlag New York Inc.
- Murdoch Affiliation
- School of Information Technology
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.54 Molecular & Cell Biology - Genetics
- 1.54.1935 Codon Usage
- Web Of Science research areas
- Biochemistry & Molecular Biology
- Evolutionary Biology
- Genetics & Heredity
- ESI research areas
- Molecular Biology & Genetics