Journal article
Ectrodactyly in A Chinese Patient Born to A Mother with Neuromyelitis Optica Spectrum Disorder
Multiple Sclerosis Journal, Vol.24(3), pp.418-419
2018
Abstract
Background: NMOSD develops primarily in women of childbearing age, and several previous studies have shown that the disorder may increase the risk of miscarriage.
Objective: To report a case of fetal malformation related to NMOSD.
Methods: We studied the case history a 30-year-old woman who was diagnosed with NMOSD who gave birth to an infant with ectrodactyly and the pathological manifestation of her placenta.
Results: The patient experienced recurrent neuritis and who was seropositive for AQP4-IgG. She became pregnant, and the fetus was found to have ectrodactyly. Histological analysis of the placenta showed moderate inflammatory infiltration.
Conclusion: It is important to be aware of NMOSD-related fetal malformation. Whether fetal malformation in NMOSD is related to inflammation and AQP4-IgG remains to be determined.
Details
- Title
- Ectrodactyly in A Chinese Patient Born to A Mother with Neuromyelitis Optica Spectrum Disorder
- Authors/Creators
- Y.Y. Chang (Author/Creator)Y.Q. Shu (Author/Creator)X.B. Sun (Author/Creator)C.F. Xu (Author/Creator)D. He (Author/Creator)L. Fang (Author/Creator)C. Chen (Author/Creator)X.Q. Hu (Author/Creator)A. Kermode (Author/Creator)Q. Wei (Author/Creator)
- Publication Details
- Multiple Sclerosis Journal, Vol.24(3), pp.418-419
- Publisher
- Sage Publications
- Identifiers
- 991005543947907891
- Copyright
- © 2018 by SAGE Publications
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Journal article
- Additional Information
- Poster presentation PACTRIMs 2017
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