Journal article
Effect of hyperoxia and vascular occlusion on tissue oxygenation measured by near infra-red spectroscopy (InSpectra™): a volunteer study
Anaesthesia, Vol.67(11), pp.1237-1241
2012
Abstract
Summary Standard cardiorespiratory monitoring may fail to detect occult tissue ischaemia. This study assessed whether a near infra-red spectroscopy tissue oxygen saturation monitor (InSpectra™) could detect progressive peripheral tissue ischaemia and whether hyperoxia may confound tissue oxygen saturation measurement. Tissue oxygen and arterial oxygen saturations were measured continuously in 30 healthy volunteers, first during a period of progressive increase in inspired oxygen concentration and subsequently during two periods of low- and high-pressure limb ischaemia. Increasing inspired oxygen concentration was associated with a small increase in mean (SD) tissue oxygen saturation of 5.3 (7.1) %, reaching a plateau between 30% and 40% inspired oxygen. The rate and magnitude of decreases in tissue oxygen saturations were greater during high- than low-pressure ischaemia with a mean (SD) desaturation rate of 3.3 (0.9) vs 1.8 (0.8) %.min-1 (p < 0.01). The dose-related association and lack of confounding by hyperoxia suggest that tissue oxygen saturation monitoring may be a useful adjunct to detect occult ischaemia.
Details
- Title
- Effect of hyperoxia and vascular occlusion on tissue oxygenation measured by near infra-red spectroscopy (InSpectra™): a volunteer study
- Authors/Creators
- B. Kyle (Author/Creator) - Queen Alexandra HospitalE. Litton (Author/Creator) - Royal Perth HospitalK.M. Ho (Author/Creator) - The University of Western Australia
- Publication Details
- Anaesthesia, Vol.67(11), pp.1237-1241
- Publisher
- Wiley-Blackwell
- Identifiers
- 991005542672407891
- Copyright
- 2012 The Association of Anaesthetists of Great Britain and Ireland.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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