Journal article
Effect of parenteral administration of oestrogen and progesterone on the glycogen metabolism of mouse morulae--early blastocysts in vivo
Reproduction, Vol.72(1), pp.67-73
1984
Abstract
Summary. Morulae—early blastocysts were pulse-labelled with radioactive glucose and subsequently transferred for 24 h to ovariectomized recipients maintained on different hormone regimens. Embryos transferred to recipients treated with progesterone utilized more glycogen than did those incubated in untreated controls. Treatment with oestrogen alone had no significant effect on glycogen turnover of transferred embryos and, when given in combination with progesterone, antagonized the effect of progesterone. Priming doses of oestrogen given >4 days before progesterone had no significant effect on the response to progesterone.
The results indicate that the high levels of progesterone circulating in the mother before implantation cause glycogen degradation in the embryo and account for the low glycogen content of uterine embryos compared to those cultured in vitro in the presence of glucose.
Details
- Title
- Effect of parenteral administration of oestrogen and progesterone on the glycogen metabolism of mouse morulae--early blastocysts in vivo
- Authors/Creators
- W.R. Edirisinghe (Author/Creator)R.G. Wales (Author/Creator)
- Publication Details
- Reproduction, Vol.72(1), pp.67-73
- Publisher
- Society for Reproduction and Fertility
- Identifiers
- 991005541943407891
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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