Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes

P.S.R. Goods; B. Dawson; G.J. Landers; C.J. Gore; K. Croft; P. Peeling

doi:10.1080/17461391.2015.1123776

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Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes

Journal article

Peer reviewed

Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes

P.S.R. Goods, B. Dawson, G.J. Landers, C.J. Gore, K. Croft and P. Peeling

European Journal of Sport Science, Vol.16(8), pp.1047-1054

2016

DOI: https://doi.org/10.1080/17461391.2015.1123776

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Abstract

This investigation examined the oxidative stress (F2-Isoprostane; F2-IsoP) and inflammatory (interleukin-6; IL-6) responses to repeat-sprint training in hypoxia (RSH). Ten trained male team sport athletes performed 3(sets)*9(repetitions)*5 s cycling sprints in simulated altitude (3000 m) and sea-level conditions. Mean and peak sprint power output (MPO and PPO) were recorded, and blood samples were collected pre-exercise, and again at 8 and 60 min post-exercise. Both MPO and PPO were significantly reduced in hypoxia (compared to sea-level) in the second (MPO: 855 ± 89 vs. 739 ± 95 W, p = .006; PPO: 1024 ± 114 vs. 895 ± 112 W, p = .010) and third (MPO: 819 ± 105 vs. 686 ± 83 W, p = .008; PPO: 985 ± 125 vs. 834 ± 99 W, p = .008) sets, respectively. IL-6 was significantly increased from pre- to 1 h post-exercise in both hypoxia (0.7 ± 0.2 vs. 2.4 ± 1.4 pg/mL, p = .004) and sea-level conditions (0.7 ± 0.2 vs. 1.6 ± 0.3 pg/mL, p < .001), with a large effect (d = 0.80) suggesting higher IL-6 levels of post-hypoxia. F2-IsoP was significantly lower 1 h post-exercise in both the hypoxic (p = .005) and sea-level (p = .002) conditions, with no differences between trials. While hypoxia can impact on exercise intensity and may result in greater post-exercise inflammation, it appears to have little effect on oxidative stress. These results indicate that team sport organisations with ready access to hypoxic training facilities could confidently administer RSH without significantly increasing the post-exercise inflammatory or oxidative stress response.

Details

Title: Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes
Authors/Creators: P.S.R. Goods (Author/Creator) - The University of Western Australia
B. Dawson (Author/Creator) - The University of Western Australia
G.J. Landers (Author/Creator) - The University of Western Australia
C.J. Gore (Author/Creator) - Flinders University
K. Croft (Author/Creator) - The University of Western Australia
P. Peeling (Author/Creator) - The University of Western Australia
Publication Details: European Journal of Sport Science, Vol.16(8), pp.1047-1054
Publisher: Taylor & Francis
Identifiers: 991005540229107891
Murdoch Affiliation: Murdoch University
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.172 Sports Science; 1.172.1727 High-Altitude Physiology
Web Of Science research areas: Sport Sciences
ESI research areas: Clinical Medicine