Journal article
Effects of oxygen concentration on the metabolism of [u-14c]glucose by mouse morulae and early blastocysts in vitro
Reproduction, Fertility and Development, Vol.1(2), pp.99-106
1989
Abstract
The utilization of the acid-soluble glycogen pool in pulse-labelled embryos was significantly enhanced during 24- and 48-h chase culture under low oxygen concentrations of 5, 2-5 and 1%. The lower the oxygen tension the greater was the turnover in the pool. The morphological development of embryos was equally as good at very low oxygen concentrations as when embryos were cultured in 5-20% oxygen. Reduction in oxygen concentration enhanced the oxidative utilization of substrate, as measured by rate of carbon dioxide production. The present study could provide an explanation for the discrepancy in glycogen content between mouse blastocysts developing in utero and in vitro and for the reported beneficial effects of low oxygen concentration during development of embryos in culture.
Details
- Title
- Effects of oxygen concentration on the metabolism of [u-14c]glucose by mouse morulae and early blastocysts in vitro
- Authors/Creators
- N.K. Khurana (Author/Creator) - Murdoch UniversityR.G. Wales (Author/Creator)
- Publication Details
- Reproduction, Fertility and Development, Vol.1(2), pp.99-106
- Publisher
- CSIRO Publishing
- Identifiers
- 991005543736307891
- Copyright
- © CSIRO 1989.
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Citation topics
- 1 Clinical & Life Sciences
- 1.81 Reproductive Biology
- 1.81.339 Embryo Development
- Web Of Science research areas
- Developmental Biology
- Reproductive Biology
- Zoology
- ESI research areas
- Plant & Animal Science