Emergence of a new disease as a result of interspecific virulence gene transfer

T.L. Friesen; E.H. Stukenbrock; Z. Liu; S. Meinhardt; H. Ling; J.D. Faris; J.B. Rasmussen; P.S. Solomon; B.A. McDonald; R.P. Oliver

doi:10.1038/ng1839

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Emergence of a new disease as a result of interspecific virulence gene transfer

Journal article

Peer reviewed

Emergence of a new disease as a result of interspecific virulence gene transfer

T.L. Friesen, E.H. Stukenbrock, Z. Liu, S. Meinhardt, H. Ling, J.D. Faris, J.B. Rasmussen, P.S. Solomon, B.A. McDonald and R.P. Oliver

Nature Genetics, Vol.38(8), pp.953-956

2006

DOI: https://doi.org/10.1038/ng1839

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Abstract

New diseases of humans, animals and plants emerge regularly. Enhanced virulence on a new host can be facilitated by the acquisition of novel virulence factors. Interspecific gene transfer is known to be a source of such virulence factors in bacterial pathogens (often manifested as pathogenicity islands in the recipient organism) and it has been speculated that interspecific transfer of virulence factors may occur in fungal pathogens. Until now, no direct support has been available for this hypothesis. Here we present evidence that a gene encoding a critical virulence factor was transferred from one species of fungal pathogen to another. This gene transfer probably occurred just before 1941, creating a pathogen population with significantly enhanced virulence and leading to the emergence of a new damaging disease of wheat.

Details

Title: Emergence of a new disease as a result of interspecific virulence gene transfer
Authors/Creators: T.L. Friesen (Author/Creator) - Northern (Arctic) Federal University
E.H. Stukenbrock (Author/Creator) - Plant (United States)
Z. Liu (Author/Creator) - North Dakota State University
S. Meinhardt (Author/Creator) - North Dakota State University
H. Ling (Author/Creator) - North Dakota State University
J.D. Faris (Author/Creator) - Northern (Arctic) Federal University
J.B. Rasmussen (Author/Creator) - North Dakota State University
P.S. Solomon (Author/Creator) - Murdoch University
B.A. McDonald (Author/Creator) - Plant (United States)
R.P. Oliver (Author/Creator) - Murdoch University
Publication Details: Nature Genetics, Vol.38(8), pp.953-956
Publisher: Nature Publishing Group
Identifiers: 991005543851807891
Murdoch Affiliation: State Agricultural Biotechnology Centre
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 3 Agriculture, Environment & Ecology; 3.97 Plant Pathology; 3.97.636 Fungal Plant Pathogens
Web Of Science research areas: Genetics & Heredity
ESI research areas: Molecular Biology & Genetics