Essentials of a new clinical practice guidance on familial hypercholesterolaemia for physicians

G.F. Watts; D.R. Sullivan; D.L. Hare; K.M. Kostner; A.E. Horton; D.A. Bell; T. Brett; R.J. Trent; N.K. Poplawski; A.C. Martin; S. Srinivasan; R.N. Justo; C.K. Chow; J. Pang; Z. Ademi; J.J. Ardill; W. Barnett; T.R. Bates; L.J. Beilin; W. Bishop; J.A. Black; A. Brown; J.R. Burnett; C.A. Bursill; A. Colley; P.M. Clifton; E.I. Ekinci; G.A. Figtree; B.H. Forge; J. Garton‐Smith; D.F. Graham; I. Hamilton‐Craig; C.R. Hamilton‐Craig; C. Heal; C.M. Hespe; A.J. Hooper; L.G. Howes; J. Ingles; E.D. Janus; N. Kangaharan; A.C. Keech; A.B. Kirke; L. Kritharides; C.V. Kyle; P. Lacaze; S.C.H. Li; S. Maticevic; B.M. McQuillan; S. Mirzaee; T.A. Mori; A.C. Morton; D.M. Colquhoun; J.C. Moullin; P.J. Nestel; K.J. Nowak; R.C. O'Brien; N. Pachter; M.M. Page; P.J. Psaltis; J. Radford; N.J. Reid; E.N. Robertson; J.D.M. Ryan; M.N. Sarkies; C.J. Schultz; C. Semsarian; L.A. Simons; C. Spinks; A.M. Tonkin; F. van Bockxmeer; K.E. Waddell‐Smith; N.C. Ward; H.D. White; A.M. Wilson; I. Winship; A.M. Woodward; S.J. Nicholls; L. Elias; W. Malan; J. Irvin; K. Lambert; A. Pedrotti

doi:10.1111/imj.15327

Back

Essentials of a new clinical practice guidance on familial hypercholesterolaemia for physicians

Journal article

Peer reviewed

Essentials of a new clinical practice guidance on familial hypercholesterolaemia for physicians

G.F. Watts, D.R. Sullivan, D.L. Hare, K.M. Kostner, A.E. Horton, D.A. Bell, T. Brett, R.J. Trent, N.K. Poplawski, A.C. Martin, …

Internal Medicine Journal, Vol.51(5), pp.769-779

2021

DOI: https://doi.org/10.1111/imj.15327

Files and links (1)

url

Link to Published Version *Subscription may be requiredView

Abstract

Familial hypercholesterolaemia (FH) is a common, heritable and preventable cause of premature coronary artery disease. New clinical practice recommendations are presented to assist practitioners in enhancing the care of all patients with FH. Core recommendations are made on the detection, diagnosis, assessment and management of adults, children and adolescents with FH. Management is under-pinned by the precepts of risk stratification, adherence to healthy lifestyles, treatment of non-cholesterol risk factors and appropriate use of low-density lipoprotein (LDL)-cholesterol-lowering therapies including statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. The recommendations need to be utilised using judicious clinical judgement and shared decision-making with patients and families. New government-funded schemes for genetic testing and use of PCSK9 inhibitors, as well as the National Health Genomics Policy Framework, will enable adoption of the recommendations. However, a comprehensive implementation science and practice strategy is required to ensure that the guidance translates into benefit for all families with FH.

Details

Title: Essentials of a new clinical practice guidance on familial hypercholesterolaemia for physicians
Authors/Creators: G.F. Watts (Author/Creator)
D.R. Sullivan (Author/Creator)
D.L. Hare (Author/Creator)
K.M. Kostner (Author/Creator)
A.E. Horton (Author/Creator)
D.A. Bell (Author/Creator)
T. Brett (Author/Creator)
R.J. Trent (Author/Creator)
N.K. Poplawski (Author/Creator)
A.C. Martin (Author/Creator)
S. Srinivasan (Author/Creator)
R.N. Justo (Author/Creator)
C.K. Chow (Author/Creator)
J. Pang (Author/Creator)
Z. Ademi (Author/Creator)
J.J. Ardill (Author/Creator)
W. Barnett (Author/Creator)
T.R. Bates (Author/Creator)
L.J. Beilin (Author/Creator)
W. Bishop (Author/Creator)
J.A. Black (Author/Creator)
A. Brown (Author/Creator)
J.R. Burnett (Author/Creator)
C.A. Bursill (Author/Creator)
A. Colley (Author/Creator)
P.M. Clifton (Author/Creator)
E.I. Ekinci (Author/Creator)
G.A. Figtree (Author/Creator)
B.H. Forge (Author/Creator)
J. Garton‐Smith (Author/Creator)
D.F. Graham (Author/Creator)
I. Hamilton‐Craig (Author/Creator)
C.R. Hamilton‐Craig (Author/Creator)
C. Heal (Author/Creator)
C.M. Hespe (Author/Creator)
A.J. Hooper (Author/Creator)
L.G. Howes (Author/Creator)
J. Ingles (Author/Creator)
E.D. Janus (Author/Creator)
N. Kangaharan (Author/Creator)
A.C. Keech (Author/Creator)
A.B. Kirke (Author/Creator)
L. Kritharides (Author/Creator)
C.V. Kyle (Author/Creator)
P. Lacaze (Author/Creator)
S.C.H. Li (Author/Creator)
S. Maticevic (Author/Creator)
B.M. McQuillan (Author/Creator)
S. Mirzaee (Author/Creator)
T.A. Mori (Author/Creator)
A.C. Morton (Author/Creator)
D.M. Colquhoun (Author/Creator)
J.C. Moullin (Author/Creator)
P.J. Nestel (Author/Creator)
K.J. Nowak (Author/Creator)
R.C. O'Brien (Author/Creator)
N. Pachter (Author/Creator)
M.M. Page (Author/Creator)
P.J. Psaltis (Author/Creator)
J. Radford (Author/Creator)
N.J. Reid (Author/Creator)
E.N. Robertson (Author/Creator)
J.D.M. Ryan (Author/Creator)
M.N. Sarkies (Author/Creator)
C.J. Schultz (Author/Creator)
C. Semsarian (Author/Creator)
L.A. Simons (Author/Creator)
C. Spinks (Author/Creator)
A.M. Tonkin (Author/Creator)
F. van Bockxmeer (Author/Creator)
K.E. Waddell‐Smith (Author/Creator)
N.C. Ward (Author/Creator)
H.D. White (Author/Creator)
A.M. Wilson (Author/Creator)
I. Winship (Author/Creator)
A.M. Woodward (Author/Creator)
S.J. Nicholls (Author/Creator)
L. Elias (Author/Creator)
W. Malan (Author/Creator)
J. Irvin (Author/Creator)
K. Lambert (Author/Creator)
A. Pedrotti (Author/Creator)
Publication Details: Internal Medicine Journal, Vol.51(5), pp.769-779
Publisher: Blackwell Publishing
Identifiers: 991005544885007891
Copyright: © 2021 Royal Australasian College of Physicians
Murdoch Affiliation: Murdoch University
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Metrics

122 Record Views

6 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.68 Lipids; 1.68.69 Lipoprotein Metabolism
Web Of Science research areas: Cardiac & Cardiovascular Systems
ESI research areas: Clinical Medicine