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Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree
Journal article   Peer reviewed

Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree

S. Iyavoo, R. Alghafri, R. Almheiri and T. Haizel
Forensic Science International: Genetics Supplement Series, Vol.7(1), pp.216-217
2019
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Abstract

The effectiveness of a rapidly mutating Y-STRs multiplex assay (RM Y-STRs) containing 13 RM Y-STR markers was compared with the AmpFℓSTR™ Yfiler™ PCR Amplification Kit (Yfiler) with conventional Y-STR markers for their efficiency in differentiating males within the same paternal lineage. Samples from 4 generations comprising 16 Dravidian males (15 father-son pairs) were analysed with both assays. Mutations were observed in 3 father-son pairs in the RM Y-STRs profiles while only 2 mutations were observed in the Y-filer profiles. Even though not many mutations were observed as anticipated, this study still emphasised the importance of RM Y-STRs when differentiation between males within the same paternal lineage is required and also indicated the need for mutation rates for different populations.

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