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Evaluation of a novel antimicrobial polymer for the control of porcine postweaning colibacillosis
Journal article   Peer reviewed

Evaluation of a novel antimicrobial polymer for the control of porcine postweaning colibacillosis

D.J. Hampson, J.R. Buddle and G.J.H. Melrose
Australian Veterinary Journal, Vol.78(2), pp.117-120
2000
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Abstract

Objective To determine whether CHEMYDERTM polymer has potential for use in the control of porcine postweaning colibacillosis (PWC). Procedure Two experiments were conducted in which 50 young pigs, either receiving CHEMYDERTM polymer in their food or not, were challenged orally with cultures of beta-haemolytic Escherichia coli immediately after weaning. Their response in terms of development of diarrhoea, and the extent of colonisation of the intestinal tract by the bacteria was monitored. In a third experiment CHEMYDERTM polymer was added to the water supply of a group of 15 pigs on a piggery where PWC was an ongoing clinical problem. The response of these pigs was compared with that of pigs vaccinated against PWC or left unmedicated. Results In both experimental infection trials the pigs receiving CHEMYDERTM polymer showed significantly reduced intestinal colonisation with the challenge strain of E coli, and, in trial 2, significantly less diarrhoea after weaning compared to pigs not receiving CHEMYDERTM polymer. In the field trial the pigs receiving CHEMYDERTM polymer had significantly less diarrhoea and required significantly less antibiotic treatment than the other two groups of pigs. Conclusion CHEMYDERTM polymer has potential for use in the control of PWC.

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Citation topics
3 Agriculture, Environment & Ecology
3.51 Dairy & Animal Sciences
3.51.208 Poultry Nutrition
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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