Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing

R.A. Fliegner; S.A. Holloway; S. Lester; C.A. McLure; R.L. Dawkins

doi:10.1111/j.1399-0039.2008.01084.x

Back

Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing

Journal article

Peer reviewed

Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing

R.A. Fliegner, S.A. Holloway, S. Lester, C.A. McLure and R.L. Dawkins

Tissue Antigens, Vol.72(2), pp.131-136

2008

DOI: https://doi.org/10.1111/j.1399-0039.2008.01084.x

Files and links (1)

url

Link to Published Version *Subscription may be requiredView

Abstract

The class II region of the major histocompatibility complex was evaluated in 25 greyhounds by sequence-based typing and the genomic matching technique (GMT). Two new DLA-DRB1 alleles were identified. Twenty-four dogs carried the DLA-DRB1*01201/DQA1*00401/DQB1*01303/DQB1*01701 haplotype, which carries two DQB1 alleles. One haplotype was identified from which DQB1 and DQA1 appeared to be deleted. The GMT enabled detection of DQB1 copy number, discrimination of the different class II haplotypes and the identification of new, possibly biologically relevant polymorphisms.

Details

Title: Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing
Authors/Creators: R.A. Fliegner (Author/Creator) - The University of Melbourne
S.A. Holloway (Author/Creator) - The University of Melbourne
S. Lester (Author/Creator) - C.Y. O’Connor ERADE Village, Canning Vale, Perth, Western Australia, Australia
C.A. McLure (Author/Creator) - Murdoch University
R.L. Dawkins (Author/Creator) - The University of Western Australia
Publication Details: Tissue Antigens, Vol.72(2), pp.131-136
Publisher: Blackwell Publishing
Identifiers: 991005544653207891
Copyright: 2008 Blackwell Munksgaard
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Metrics

20 Record Views

4 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.6 Immunology; 1.6.607 MHC Diversity
Web Of Science research areas: Cell Biology; Immunology; Pathology
ESI research areas: Molecular Biology & Genetics