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CC BY V4.0, Open Access
Journal article
Exercise responses to perceptually regulated high intensity interval exercise with continuous and intermittent hypoxia in inactive overweight individuals
Experimental physiology, Vol.110(6), pp.832-843
2025
PMID: 39937576
Appears in Open Access via Read & Publish Agreements
Abstract
To investigate the acute effects of hypoxia applied during discrete work and recovery phases of a perceptually regulated, high-intensity interval exercise (HIIE) on external and internal loads in inactive overweight individuals. On separate days, 18 inactive overweight (28.7 ± 3.3 kg m−2; 31 ± 8 years) men and women completed a cycling HIIE protocol (6 × 1 min intervals with 4 min active recovery, maintaining a perceived rating of exertion of 16 and 10 during work and recovery, respectively, on the 6–20 Borg scale) in randomized conditions: normoxia (NN), normobaric hypoxia (inspired O2 fraction ∼0.14) during both work and recovery (HH), hypoxia during recovery (NH) and hypoxia during work only (HN). Markers of external (relative mean power output, MPO) and internal load (blood lactate concentration, heart rate and tissue saturation index (TSI)) were measured. MPO was lower in HH compared to NN, NH and HN (all P < 0.001), with HN also being lower than NN (P < 0.001) and NH (P < 0.023). Heart rate was higher in HN than NN, HH and NH (all P < 0.001). Blood lactate response was higher in NN than HH (P = 0.003) and NH (P = 0.008). Changes in the TSI area above the curve were greater in HN relative to NN, HH and NH (all P < 0.001). Hypoxia applied intermittently during the work or recovery phases may mitigate the declines in mechanical output observed when exercise is performed in continuous hypoxia, although hypoxia implemented during the work phase resulted in elevated heart rate and lactate response. Specifically, exercise performance largely comparable to that in normoxia can be achieved when hypoxia is implemented exclusively during recovery.
Details
- Title
- Exercise responses to perceptually regulated high intensity interval exercise with continuous and intermittent hypoxia in inactive overweight individuals
- Authors/Creators
- Jacky Soo - Murdoch UniversityPaul Goods - Murdoch University, Centre for Healthy AgeingOlivier Girard - The University of Western AustraliaLouise Deldicque - UCLouvainNathan G. Lawler - Murdoch University, Health Futures InstituteTimothy J. Fairchild - Murdoch University, Centre for Molecular Medicine and Innovative Therapeutics
- Publication Details
- Experimental physiology, Vol.110(6), pp.832-843
- Publisher
- John Wiley & Sons Ltd on behalf of The Physiological Society.
- Number of pages
- 12
- Identifiers
- 991005743944407891
- Copyright
- © 2025 The Author(s).
- Murdoch Affiliation
- Centre for Healthy Ageing; Health Futures Institute; School of Allied Health; Centre for Computational and Systems Medicine; Centre for Molecular Medicine and Innovative Therapeutics
- Language
- English
- Resource Type
- Journal article
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- Domestic collaboration
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- Citation topics
- 1 Clinical & Life Sciences
- 1.172 Sports Science
- 1.172.1727 High-Altitude Physiology
- Web Of Science research areas
- Physiology
- ESI research areas
- Biology & Biochemistry