Journal article
Experimental Trypanosoma evansi infection in the goat. I. Clinical signs and clinical pathology
Journal of Comparative Pathology, Vol.133(4), pp.261-266
2005
Abstract
A strain of Trypanosoma evansi isolated from an equine case of surra in Mindanao, Philippines was used to infect intravenously two groups (A and B) of five male goats aged 8–10 months. Animals of groups A and B received 5000 and 50 000 trypanosomes, respectively, and five further animals (group C) served as uninfected controls. Four of the 10 infected goats died 8–78 days after inoculation. Group C goats gained weight (mean 22.8 g/day) while infected goats in groups A and B lost weight (means of 21.4 and 45.0 g/day, respectively). Parasitaemia fluctuated regularly between peaks and troughs, with repeated periods of about 6 days during which no trypanosomes were detected in the blood. Clinical signs and clinico-pathological changes in infected goats were not pathognomonic in the absence of parasites in the blood, and leucocytosis was not a reliable indicator of infection. It was concluded that in endemic areas fluctuating fever, progressive emaciation, anaemia, coughing, testicular enlargement and diarrhoea are suggestive of surra; confirmation, however, may necessitate examination of blood every few days for trypanosomes, and possibly other diagnostic tests.
Details
- Title
- Experimental Trypanosoma evansi infection in the goat. I. Clinical signs and clinical pathology
- Authors/Creators
- A.P. Dargantes (Author/Creator) - Central Mindanao UniversityS.A. Reid (Author/Creator) - Murdoch UniversityD.B. Copeman (Author/Creator) - Australian Institute of Tropical Health and Medicine
- Publication Details
- Journal of Comparative Pathology, Vol.133(4), pp.261-266
- Publisher
- Elsevier BV
- Identifiers
- 991005541428507891
- Copyright
- © 2005 Elsevier Ltd
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.261 Parasitology - Trypanosoma & Leishmania
- 1.261.596 Trypanosoma Biology
- Web Of Science research areas
- Pathology
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science