Journal article
Extended spectrum cephalosporins and Clostridium difficile
Journal of Antimicrobial Chemotherapy, Vol.23(6), pp.929-931
1989
Abstract
There is little information about how commonly the newer cephalosporins cause diarrhoea due to Clostridium difficile. In this study of 111 patients with C. difficile-associated diarrhoea, 106 had received antimicrobial agents in the four weeks before detection of C. difficile. The relative risk for each antimicrobial agent was greatest with clindamycin, followed by cefotaxime, cephamandole and ceftriaxone. There was no statistically significant difference in risk between the cephalosporins evaluated. Narrower spectrum penicillins, anti-pseudomonal penicillins and aminoglycosides were not potent inciting agents.
Details
- Title
- Extended spectrum cephalosporins and Clostridium difficile
- Authors/Creators
- C.L. Golledge (Author/Creator) - Sir Charles Gairdner HospitalT. McKenzie (Author/Creator) - Sir Charles Gairdner HospitalT.V. Riley (Author/Creator) - The University of Western Australia
- Publication Details
- Journal of Antimicrobial Chemotherapy, Vol.23(6), pp.929-931
- Publisher
- Oxford University Press
- Identifiers
- 991005543060607891
- Copyright
- © 1989 The British Society for Antimicrobial Chemotherapy
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.120 Inflammatory Bowel Diseases & Infections
- 1.120.1133 Clostridium Infections
- Web Of Science research areas
- Infectious Diseases
- Microbiology
- Pharmacology & Pharmacy
- ESI research areas
- Pharmacology & Toxicology