Journal article
Feline pemphigus foliaceus: Original case series and a comprehensive literature review
BMC Veterinary Research, Vol.15, Article number: 22
2019
Abstract
Background
Since the first description of feline pemphigus foliaceus (PF) more than 30 years ago, numerous case reports have been published, while larger case series have remained rare. This large body of information, if extrapolated, could address clinical discrepancies and expand our knowledge about the treatment of feline PF.
This manuscript reviews cases of feline PF published between 1950 and 2016 and adds additional 35 original cases to provide further insight into the clinical aspect and treatment outcome of this disease.
Results
Feline PF, while being a primary acantholytic pustular dermatosis, presents most often with crusts and erosions that predominantly affect the face and feet. More than half of cats with active disease exhibits non-dermatological signs such as lethargy, fever and/or anorexia. The prognosis of feline PF is good as the majority of cats rapidly achieve disease control even with the most basic treatment such as glucocorticoid monotherapy. Most PF-affected cats, however, require long-term treatment and, like other autoimmune diseases, feline PF has a tendency to relapse spontaneously or with treatment changes.
Conclusions
Therefore, despite the overall good prognosis cats with PF can be given, owners should be informed and prepared for these circumstances, which may reduce the risk of euthanasia in the case of disease relapse, and improve treatment compliance.
Details
- Title
- Feline pemphigus foliaceus: Original case series and a comprehensive literature review
- Authors/Creators
- P. Bizikova (Author/Creator)A. Burrows (Author/Creator)
- Publication Details
- BMC Veterinary Research, Vol.15, Article number: 22
- Publisher
- BioMed Central
- Identifiers
- 991005545042307891
- Copyright
- © 2019 The Author(s)
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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- 1.239 Tissue Barriers
- 1.239.1135 Autoimmune Blistering Diseases
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- Veterinary Sciences
- ESI research areas
- Plant & Animal Science