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Carriage of intestinal spirochaetes by humans: epidemiological data from Western Australia
Journal article   Open access   Peer reviewed

Carriage of intestinal spirochaetes by humans: epidemiological data from Western Australia

C.J. Brooke, A.N. Clair, A.S.J. Mikosza, T.V. Riley and D.J. Hampson
Epidemiology and Infection, Vol.127(02), pp.369-374
2001
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Abstract

The purpose of this study was to investigate carriage of intestinal spirochaetes by selected population groups in Western Australia. Stool specimens from 293 rural patients with gastrointestinal disorders, and from 227 healthy migrants from developing countries were cultured. Spirochaete isolates were identified using PCR, and typed by pulsed field gel electrophoresis (PFGE). Brachyspira aalborgi was not isolated. Brachyspira pilosicoli was recovered from 15 rural patients, all Aboriginal. Prevalence was 9·9% in 151 Aboriginals and 0% in 142 non-Aboriginals. Carriage of B. pilosicoli amongst migrants was 10·6% (24/227). Carriage was significantly increased in Aboriginal children aged 2–5 years (P = 0·0027) and in migrant individuals from the Middle East and Africa (P = 0·0034). Carriage was significantly associated with detection of faecal protozoa in both Aboriginals (P = 0·0021) and migrants (P = 0·012). PFGE results indicated that the B. pilosicoli strains were genetically diverse.

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Domestic collaboration
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1 Clinical & Life Sciences
1.248 Sexually Transmitted Infections
1.248.2445 Lawsonia Intracellularis
Web Of Science research areas
Infectious Diseases
Public, Environmental & Occupational Health
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Social Sciences, general
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