Logo image
Functional molecular markers in barley: Development and applications
Journal article   Open access   Peer reviewed

Functional molecular markers in barley: Development and applications

R.K. Varshney, M. Prasad, R. Kota, R. Sigmund, A. Börner, J. Valkoun, U. Scholz, N. Stein and A. Graner
Czech Journal of Genetics and Plant Breeding, Vol.41, pp.128-133
2005
pdf
Barley.pdfDownloadView
Published (Version of Record) Open Access
url
Free to Read *No subscription requiredView

Abstract

The availability of sequence data from large-scale EST (expressed sequence tag) projects has made it possible to develop markers directly from genes. In order to develop functional markers and the preparation of a transcript map (integrating of genes/transcripts to genetic map) of barley, more than 1000 ESTs/cDNAs including 589 RFLP (Restriction Fragment Length Polymorphism), 255 SNP (Single Nucleotide Polymorphism) and 185 SSR (Simple Sequence Repeat or microsatellite) markers have been developed. These markers provide a good resource for a variety of purposes including pedigree analysis, the study of marker-trait associations and comparative mapping in other cereals. A computational study suggests a theoretical transferability of barley markers to wheat (95.2%), rice (70.3%), maize (69.3%), sorghum (65.9%), rye (38.1%) and even to dicot species (~16%). Comparative mapping of 9 barley EST-SSRs in rye suggested the potential of barley markers to saturate the genetic maps of minor crop species having a shortage of molecular markers on their genetic maps. A comparison of 50 SSR and 50 SNP marker data for cladistic analysis on a set of six diverse barley genotypes showed that both marker types yield similar groupings. Therefore, gene-derived markers are a good resource for sampling the functional diversity in natural germplasm collection or breeding material.

Details

Metrics

136 File views/ downloads
40 Record Views
Logo image