Journal article
Functional roles of neuronal nitric oxide synthase in neurodegenerative diseases and mood disorders
Current Alzheimer Research, Vol.18(10), pp.831-840
2021
Abstract
Nitric oxide synthase (NOS) is well known for its involvement in the regulation of the nervous, cardiovascular, and immune systems. Neuronal NOS (nNOS) is the most characterized NOS among all the isoforms. It accounts for most of the production of nitric oxide (NO) in the nervous system required for synaptic transmission and neuroplasticity. Previous studies have described the localization of nNOS in specific brain regions of interest. There is substantial evidence in the literature suggesting that nNOS signaling has significant involvement in several disease pathologies. However, the association between brain nNOS expression profiles and disease remains largely unknown. In this review, we attempt to delineate the contribution of nNOS signaling in memory and mood disorders in order to achieve a better understanding of nNOS in disease modulation.
Details
- Title
- Functional roles of neuronal nitric oxide synthase in neurodegenerative diseases and mood disorders
- Authors/Creators
- C.H. Poon (Author/Creator) - University of Hong KongK.C. Tsui (Author/Creator) - University of Hong KongS.C. Chau (Author/Creator) - University of Hong KongP.S. Chong (Author/Creator) - University of Hong KongS.W.Y. Lui (Author/Creator) - University of Hong KongL. Aquili (Author/Creator) - University of Hong KongK.H. Wong (Author/Creator) - University of Hong KongL.W. Lim (Author/Creator) - University of Hong Kong
- Publication Details
- Current Alzheimer Research, Vol.18(10), pp.831-840
- Publisher
- Bentham Science Publishers
- Identifiers
- 991005543586907891
- Copyright
- © 2021 Bentham Science Publishers
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.127 Molecular & Cell Biology - Pharmacology
- 1.127.87 Nitric Oxide Roles
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior