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Journal article
Garlic bioactive substances and their therapeutic applications for improving human health: a comprehensive review
Frontiers in immunology, Vol.15, 1277074
2024
Abstract
Garlic ( Allium sativum L.) is a widely abundant spice, known for its aroma and pungent flavor. It contains several bioactive compounds and offers a wide range of health benefits to humans, including those pertaining to nutrition, physiology, and medicine. Therefore, garlic is considered as one of the most effective disease-preventive diets. Many in vitro and in vivo studies have reported the sulfur-containing compounds, allicin and ajoene, for their effective anticancer, anti-diabetic, anti-inflammatory, antioxidant, antimicrobial, immune-boosting, and cardioprotective properties. As a rich natural source of bioactive compounds, including polysaccharides, saponins, tannins, linalool, geraniol, phellandrene, β-phellandrene, ajoene, alliin, S-allyl-mercapto cysteine, and β-phellandrene, garlic has many therapeutic applications and may play a role in drug development against various human diseases. In the current review, garlic and its major bioactive components along with their biological function and mechanisms of action for their role in disease prevention and therapy are discussed.
Details
- Title
- Garlic bioactive substances and their therapeutic applications for improving human health: a comprehensive review
- Authors/Creators
- Mohamed T. El-SaadonyAhmed M. Saad - Zagazig UniversitySameh A. Korma - Zagazig UniversityHeba M. Salem - Cairo UniversityTaia A. Abd El-MageedSamar Sami Alkafaas - Tanta UniversityMohamed I. Elsalahaty - Tanta UniversitySara Samy Elkafas - Menoufia UniversityWalid F. A. Mosa - Alexandria UniversityAhmed Ezzat Ahmed - King Khalid UniversityBetty T. Mathew - United Arab Emirates UniversityNoor A. Albastaki - United Arab Emirates UniversityAysha A. Alkuwaiti - United Arab Emirates UniversityMarawan K. El-Tarabily - University of DebrecenSynan F. AbuQamar - United Arab Emirates UniversityKhaled A. El-TarabilySalam A. Ibrahim - North Carolina Agricultural and Technical State University
- Publication Details
- Frontiers in immunology, Vol.15, 1277074
- Publisher
- Frontiers Media S.A.
- Identifiers
- 991005678668107891
- Copyright
- © 2024 El-Saadony, Saad, Korma, Salem, Abd El-Mageed, Alkafaas, Elsalahaty, Elkafas, Mosa, Ahmed, Mathew, Albastaki, Alkuwaiti, El-Tarabily, AbuQamar, El-Tarabily and Ibrahim
- Murdoch Affiliation
- Centre for Terrestrial Ecosystem Science and Sustainability
- Language
- English
- Resource Type
- Journal article
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