Journal article
Gene therapy and molecular approaches to the treatment of hereditary muscular disorders
Current Opinion in Neurology, Vol.13(5), pp.553-560
2000
Abstract
Gene therapy for inherited muscle disease is an active area of research and development. Initial emphasis has been on gene replacement but alternative approaches are increasingly being considered in order to overcome difficulties, such as the immune rejection of transduced cells, the need for appropriate and tissue-specific control of expression, and the requirement for systemic spread in some conditions. However, the most significant obstacles to the clinical success of gene therapy are still the lack of efficiency and accuracy of gene medicine delivery.
Details
- Title
- Gene therapy and molecular approaches to the treatment of hereditary muscular disorders
- Authors/Creators
- S. Fletcher (Author/Creator) - The University of Western AustraliaS.D. Wilton (Author/Creator) - Centre for Neuromuscular and Neurological DisordersJ.Mc.C. Howell (Author/Creator)
- Publication Details
- Current Opinion in Neurology, Vol.13(5), pp.553-560
- Publisher
- Lippincott Williams & Wilkins
- Identifiers
- 991005540907907891
- Copyright
- © 2000 Lippincott Williams and Wilkins.
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.255 Musculoskeletal Disorders
- 1.255.628 Duchenne Muscular Dystrophy
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior