Journal article
Genetic Diversity and Population Structure of Cryptosporidium
Trends in Parasitology, Vol.34(11), pp.997-1011
2018
Abstract
Cryptosporidium species differ in host range. Parasite–host coevolution, host adaptation, and geographic segregation have led to the formation of subtype families with unique phenotypic traits within the major human-pathogenic species C. parvum and C. hominis. Transmission intensity, genetic diversity, and occurrence of genetic recombination and selective pressure have further shaped their population genetic structures. Panmixia appears to be common within the zoonotic C. parvum, especially its hypertransmissible IIaA15G2R1 subtype. Genetic recombination in C. hominis, in contrast, is more restricted to virulent subtypes, especially IbA10G2. Nonhuman primates and equine animals are commonly infected with genetically divergent C. hominis populations. Systematic studies of these and other host-adapted Cryptosporidium spp. are likely leading to improved understanding of population structures underlying various transmission patterns and intensities of Cryptosporidium.
Details
- Title
- Genetic Diversity and Population Structure of Cryptosporidium
- Authors/Creators
- Y. Feng (Author/Creator) - South China Agricultural UniversityU. Ryan (Author/Creator) - Murdoch UniversityL. Xiao (Author/Creator) - South China Agricultural University
- Publication Details
- Trends in Parasitology, Vol.34(11), pp.997-1011
- Publisher
- Elsevier Ltd
- Identifiers
- 991005540082807891
- Copyright
- © 2018 Elsevier Ltd
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Parasitology
- ESI research areas
- Microbiology