Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease

J.M. van der Walt; E.R. Martin; W.K. Scott; F. Zhang; M.A. Nance; R.L. Watts; J.P. Hubble; J.L. Haines; W.C. Koller; K. Lyons; R. Pahwa; M.B. Stern; A. Colcher; B.C. Hiner; J. Jankovic; W.G. Ondo; F.H. Allen; C.G. Goetz; G.W. Small; F. Mastaglia; A.D. Roses; J.M. Stajich; M.W. Booze; K. Fujiwara; R.A. Gibson; L.T. Middleton; B.L. Scott; M.A. Pericak-Vance; J.M. Vance

doi:10.1212/01.WNL.0000055929.84668.9A

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Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease

Journal article

Peer reviewed

Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease

J.M. van der Walt, E.R. Martin, W.K. Scott, F. Zhang, M.A. Nance, R.L. Watts, J.P. Hubble, J.L. Haines, W.C. Koller, K. Lyons, …

Neurology, Vol.60(7), pp.1189-1191

2003

DOI: https://doi.org/10.1212/01.WNL.0000055929.84668.9A

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Abstract

Recently, the authors demonstrated linkage in idiopathic PD to a region on chromosome 8p that contains the N-acetyltransferase genes, NAT1 and NAT2. The authors examined NAT1 and NAT2 for association with PD using family-based association methods and single nucleotide polymorphisms (SNPs). The authors did not find evidence for association with increased risk for PD between any individual NAT1 or NAT2 SNP or acetylation haplotype (N = 397 families, 1,580 individuals).

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Title: Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease
Authors/Creators: J.M. van der Walt (Author/Creator) - Duke University
E.R. Martin (Author/Creator) - Duke University
W.K. Scott (Author/Creator) - Duke University
F. Zhang (Author/Creator) - Duke University
M.A. Nance (Author/Creator) - Struthers Parkinson Center
R.L. Watts (Author/Creator) - Emory University
J.P. Hubble (Author/Creator) - The Ohio State University
J.L. Haines (Author/Creator) - VA Medical Center
W.C. Koller (Author/Creator) - University of Miami*
K. Lyons (Author/Creator) - University of Miami*
R. Pahwa (Author/Creator) - University of Kansas
M.B. Stern (Author/Creator) - University of Pennsylvania
A. Colcher (Author/Creator) - University of Pennsylvania
B.C. Hiner (Author/Creator) - Marshfield Clinic
J. Jankovic (Author/Creator) - Baylor College of Medicine
W.G. Ondo (Author/Creator) - Baylor College of Medicine
F.H. Allen (Author/Creator) - Carolina Neurological Clinic
C.G. Goetz (Author/Creator) - Rush University
G.W. Small (Author/Creator) - University of California, Los Angeles
F. Mastaglia (Author/Creator) - The University of Western Australia
A.D. Roses (Author/Creator) - (GlaxoSmithKline)
J.M. Stajich (Author/Creator) - Duke University
M.W. Booze (Author/Creator) - Duke University
K. Fujiwara (Author/Creator) - Duke University
R.A. Gibson (Author/Creator)
L.T. Middleton (Author/Creator)
B.L. Scott (Author/Creator) - Duke University
M.A. Pericak-Vance (Author/Creator) - Duke University
J.M. Vance (Author/Creator) - Duke University
Publication Details: Neurology, Vol.60(7), pp.1189-1191
Publisher: Lippincott Williams & Wilkins
Identifiers: 991005545449507891
Copyright: © 2003 American Academy of Neurology
Murdoch Affiliation: Murdoch University
Language: English
Resource Type: Journal article

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Collaboration types: Industry collaboration; Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.52 Neurodegenerative Diseases; 1.52.67 Parkinson's Disease
Web Of Science research areas: Clinical Neurology
ESI research areas: Neuroscience & Behavior