Journal article
Genomic characterisation of linezolid-resistant Enterococcus faecalis from Western Australia 2016–2021
Pathology, Vol.55(3), pp.397-399
2023
PMID: 36085088
Abstract
To the Editor,
Linezolid (LNZ) is an oxazolidinone antibiotic and a drug of last resort used to treat infections caused by Gram-positive pathogens that are resistant to multiple classes of antibiotics. In Australia, LNZ was introduced in 2002 and is currently reserved to treat suspected or proven infections caused by methicillin-resistant staphylococci or vancomycin-resistant enterococci. Despite restricted use, LNZ resistance has emerged worldwide, threatening the effective treatment of multidrug-resistant bacterial infections.1 In Australia, LNZ-resistant enterococci (LRE) are monitored and reported by each state and territory to the National Alert System for Critical Antimicrobial Resistances (CARAlert), as part of the AURA (Antimicrobial Use and Resistance in Australia) surveillance system...
Details
- Title
- Genomic characterisation of linezolid-resistant Enterococcus faecalis from Western Australia 2016–2021
- Authors/Creators
- Shakeel Mowlaboccus - Murdoch UniversityDenise A. Daley - Fiona Stanley HospitalGeoffrey W. Coombs - Murdoch University
- Publication Details
- Pathology, Vol.55(3), pp.397-399
- Publisher
- Elsevier B.V
- Identifiers
- 991005579433707891
- Copyright
- © 2022 Royal College of Pathologists of Australasia
- Murdoch Affiliation
- Centre for Biosecurity and One Health
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.23 Antibiotics & Antimicrobials
- 1.23.173 MRSA and VRE
- Web Of Science research areas
- Pathology
- ESI research areas
- Clinical Medicine