Journal article
Genomic characterization of coagulase-negative staphylococci including methicillin-resistant Staphylococcus sciuri causing bovine mastitis
Veterinary Microbiology, Vol.219, pp.17-22
2018
Abstract
Methicillin-resistant coagulase-negative staphylococci (MRCoNS) have recently emerged as a significant cause of bovine mastitis worldwide. Here we describe the isolation of MRCoNS from cases of bovine mastitis from a single dairy farm in Australia. Fourteen CoNS isolates were identified as MRCoNS on the basis of having an oxacillin MIC of ≥0.5 μg/mL. The isolates were speciated as S. chromogenes (n = 1) S. fleurettii (n = 1), S. haemolyticus (n = 2), S. sciuri (n = 5), S. simulans (n = 1) S. succinus (n = 2) and S. xylosus (n = 2). Five of the isolates (S. fleuretti, S. haemolyticus S. sciuri and two S. succinus) were mecA-positive. We also detected a previously described S. sciuri mecA homolog in four oxacillin-resistant S. sciuri isolates. The remainder of the putative MRCoNS did not contain any mecA-related resistance determinants in their genomes. Comparative genomic analysis of three previously published S. sciuri isolates, from humans, a squirrel and a cereal crop (rice), and a representative isolate from our study demonstrated clustering and a high degree of genetic homogeneity (>95%), suggesting S. sciuri has low host specificity. In conclusion, CoNS, in particular S. sciuri, may act as a reservoir for SCCmec elements that can easily be spread between different host species by direct cross-infection.
Details
- Title
- Genomic characterization of coagulase-negative staphylococci including methicillin-resistant Staphylococcus sciuri causing bovine mastitis
- Authors/Creators
- M. Khazandi (Author/Creator) - The University of AdelaideA.A-B Al-Farha (Author/Creator) - Northern Technical UniversityG.W. Coombs (Author/Creator) - The University of Western AustraliaM. O’Dea (Author/Creator) - Murdoch UniversityS. Pang (Author/Creator) - Murdoch UniversityD.J. Trott (Author/Creator) - The University of AdelaideR.R. Aviles (Author/Creator) - The University of AdelaideF. Hemmatzadeh (Author/Creator) - The University of AdelaideH. Venter (Author/Creator) - University of South AustraliaA.D. Ogunniyi (Author/Creator) - The University of AdelaideA. Hoare (Author/Creator) - South East Vets, Mount Gambier, South Australia, Australia.S. Abraham (Author/Creator) - Murdoch UniversityK.R. Petrovski (Author/Creator) - The University of Adelaide
- Publication Details
- Veterinary Microbiology, Vol.219, pp.17-22
- Publisher
- Elsevier BV
- Identifiers
- 991005542216207891
- Copyright
- © 2018 Elsevier B.V.
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
49 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.23 Antibiotics & Antimicrobials
- 1.23.173 MRSA and VRE
- Web Of Science research areas
- Microbiology
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science