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Genomic evolution in domestic cattle: Ancestral haplotypes and healthy beef
Journal article   Open access   Peer reviewed

Genomic evolution in domestic cattle: Ancestral haplotypes and healthy beef

J.F. Williamson, E.J. Steele, S. Lester, O. Kalai, J.A. Millman, L. Wolrige, D. Bayard, C. McLure and R.L. Dawkins
Genomics, Vol.97(5), pp.304-312
2011
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Abstract

We have identified numerous Ancestral Haplotypes encoding a 14-Mb region of Bota C19. Three are frequent in Simmental, Angus and Wagyu and have been conserved since common progenitor populations. Others are more relevant to the differences between these 3 breeds including fat content and distribution in muscle. SREBF1 and Growth Hormone, which have been implicated in the production of healthy beef, are included within these haplotypes. However, we conclude that alleles at these 2 loci are less important than other sequences within the haplotypes. Identification of breeds and hybrids is improved by using haplotypes rather than individual alleles.

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Collaboration types
Industry collaboration
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.6 Immunology
1.6.607 MHC Diversity
Web Of Science research areas
Biotechnology & Applied Microbiology
Genetics & Heredity
ESI research areas
Molecular Biology & Genetics
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