Journal article
Genomic islands and mobilome demonstrate a potential pathogen, the Plesiomonas shigelloides, as in Nile tilapia (Oreochromis niloticus)
The microbe, Vol.8, 100441
2025
Abstract
Plesiomonas shigelloides is a common opportunistic pathogen of fish that may result in significant economic losses during outbreak periods. The infection is revealed by several clinical signs, including pericarditis, multifocal necrosis, hepatic atrophy, ulcerative lesions and other pathological changes, which may result in a reduction in the number of economically viable animals on fish farms. In humans, P. shigelloides infections are associated with diarrheic cases resulting from the consumption of contaminated food. These facts justify further study of the species pathogenicity, which is not yet well-established owing to the recent taxonomic classification. Considering the aforementioned information, the main goal of this research was to characterize the virulence and antimicrobial resistance factors present in four P. shigelloides strains isolated from aquatic organisms in Brazil. To gain a deeper understanding of the genomic characteristics of the subjects, the following methodology was employed: the genomic similarity of the strains was evaluated through the pyANI method; the phylogenomic evaluation was performed by OrthoFinder; GIPSy software was used for genomic island search; and PanViTa was employed to search for virulence and resistance factors. The results suggest the presence of multiple virulence factors (51) and antimicrobial resistance genes (12) in the genomes of the main isolates. This is the first genomic study of P. shigelloides exploring the potential pathogenicity in Nile tilapia in the northeast Brazil.
Details
- Title
- Genomic islands and mobilome demonstrate a potential pathogen, the Plesiomonas shigelloides, as in Nile tilapia (Oreochromis niloticus)
- Authors/Creators
- Flavia Figueira Aburjaile - Univ Fed Minas Gerais, Vet Sch, Prevent Vet Med Dept, Lab Integrat Bioinformat, BR-31270901 Belo Horizonte, MG, BrazilDiego Lucas Neres Rodrigues - Univ Fed Minas Gerais, Vet Sch, Prevent Vet Med Dept, Lab Integrat Bioinformat, BR-31270901 Belo Horizonte, MG, BrazilJuan Carlos Ariute - Univ Fed Minas Gerais, Vet Sch, Prevent Vet Med Dept, Lab Integrat Bioinformat, BR-31270901 Belo Horizonte, MG, BrazilMariana Silva Batista - Univ Fed Minas Gerais, Vet Sch, Prevent Vet Med Dept, Lab Integrat Bioinformat, BR-31270901 Belo Horizonte, MG, BrazilLigia Carolina da Silva Prado - Univ Fed Triangulo Mineiro, Dept Microbiol Immunol & Parasitol, BR-38025180 Uberaba, MG, BrazilSilvia de Carli - Univ Fed Rio Grande do Sul, Dept Vet Clin Pathol, Lab Vet Bacteriol, Porto Alegre, RS, BrazilSheila da Silva - Univ Fed Rio de Janeiro, Postgrad Program Plant Biotechnol & Bioproc, Rio De Janeiro, BrazilJoa Ricardo Vidal Amaral - Univ Fed Rio de Janeiro, Postgrad Program Plant Biotechnol & Bioproc, Rio De Janeiro, BrazilThiago Sousa - Univ Fed Minas Gerais, Inst Biol Sci, Lab Cellular & Mol Genet, BR-31270901 Belo Horizonte, MG, BrazilRaquel Hurtado - Univ Fed Minas Gerais, Inst Biol Sci, Lab Cellular & Mol Genet, BR-31270901 Belo Horizonte, MG, BrazilEdilson do Carmo Marins Jr - Fed Univ Vale Sao Francisco Univasf, Ctr Open Access Genom Anal CALAnGO, BR-56304917 Petrolina, PE, BrazilRodrigo Dias de Oliveira Carvalho - Univ Fed Minas Gerais, Inst Biol Sci, Lab Cellular & Mol Genet, BR-31270901 Belo Horizonte, MG, BrazilAndrew Macrae - Univ Fed Rio de Janeiro, Postgrad Program Plant Biotechnol & Bioproc, Rio De Janeiro, BrazilBertram Brenig - Univ Gottingen, Inst Vet Med, D-37077 Gottingen, Niedersachsen, GermanyRommel Ramos - Fed Univ Para, Inst Biol Sci, Biol Engn Lab, BR-66075110 Belem, Para, BrazilAristoteles Goes-Neto - Univ Fed Minas Gerais, Inst Biol Sci, Lab Mol Computat Biol Fungi, BR-31270901 Belo Horizonte, MG, BrazilGisele Veneroni Gouveia - Fed Univ Vale Sao Francisco Univasf, Ctr Open Access Genom Anal CALAnGO, BR-56304917 Petrolina, PE, BrazilJoao Jose de Simoni Gouveia - Fed Univ Vale Sao Francisco Univasf, Ctr Open Access Genom Anal CALAnGO, BR-56304917 Petrolina, PE, BrazilUlisses de Padua Pereira - State Univ Londrina UEL, Lab Fish Bacteriol LABBEP, Londrina, Parana, BrazilSelma Soares de Oliveira - Univ Fed Rio de Janeiro, Postgrad Program Plant Biotechnol & Bioproc, Rio De Janeiro, BrazilFranciele Maboni - Univ Fed Rio Grande do Sul, Dept Vet Clin Pathol, Lab Vet Bacteriol, Porto Alegre, RS, BrazilVasco Azevedo - Univ Fed Minas Gerais, Inst Biol Sci, Lab Cellular & Mol Genet, BR-31270901 Belo Horizonte, MG, BrazilSiomar de Castro Soares - Univ Fed Triangulo Mineiro, Dept Microbiol Immunol & Parasitol, BR-38025180 Uberaba, MG, BrazilMateus Matiuzzi - Fed Univ Vale Sao Francisco Univasf, Ctr Open Access Genom Anal CALAnGO, BR-56304917 Petrolina, PE, Brazil
- Publication Details
- The microbe, Vol.8, 100441
- Publisher
- Elsevier
- Number of pages
- 12
- Grant note
- CNPq; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) CAPES; Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) 27683; 2019-2025; 30201; 2022; 30563 / FAPEMIG; Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG)
- Identifiers
- 991005894544907891
- Copyright
- © 2025
- Murdoch Affiliation
- Food Futures Institute
- Language
- English
- Resource Type
- Journal article
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