Journal article
Genomic sequence analysis identifies Jembrana disease virus as a new bovine lentivirus
Journal of General Virology, Vol.76(1), pp.189-192
1995
Abstract
Jembrana disease virus, the cause of an acute, severe disease in Bali (Bos javanicus) cattle in Indonesia was recently identified as a retrovirus, and possibly a lentivirus. We have produced sequence data representing 598 bp of the pol gene, amplified by PCR from viral cDNA using broadly reactive universal primers for retroviruses and more specific genus-reactive primers for lentiviruses. When the sequence data were compared with that of known lentiviruses and other bovine retroviruses, the closest alignment was with bovine immunodeficiency-like lentivirus (BIV), showing 74% nucleotide sequence identity. This confirmed that JDV is a lentivirus and that it is distinguishable from BIV. The pathogenesis of Jembrana disease is most unusual for a lentivirus infection and differs markedly from that reported for BIV infection.
Details
- Title
- Genomic sequence analysis identifies Jembrana disease virus as a new bovine lentivirus
- Authors/Creators
- B.J. Chadwick (Author/Creator) - Murdoch UniversityR.J. Coelen (Author/Creator)L.M. Sammels (Author/Creator)G. Kertayadnya (Author/Creator)G.E. Wilcox (Author/Creator)
- Publication Details
- Journal of General Virology, Vol.76(1), pp.189-192
- Publisher
- Society for General Microbiology
- Identifiers
- 991005540342407891
- Copyright
- © 1995 SGM
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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