Journal article
Giardia — from genome to proteome
Advances in Parasitology Volume 78, Vol.78, pp.57-95
2012
Abstract
In this review, the current status of genomic and proteomic research on Giardia is examined in terms of evolutionary biology, phylogenetic relationships and taxonomy. The review also describes how characterising genetic variation in Giardia from numerous hosts and endemic areas has provided a better understanding of life cycle patterns, transmission and the epidemiology of Giardia infections in humans, domestic animals and wildlife. Some progress has been made in relating genomic information to the phenotype of Giardia, and as a consequence, new information has been obtained on aspects of developmental biology and the host-parasite relationship. However, deficiencies remain in our understanding of pathogenesis and host specificity, highlighting the limitations of currently available genomic datasets.
Details
- Title
- Giardia — from genome to proteome
- Authors/Creators
- R.C.A. Thompson (Author/Creator) - Murdoch UniversityP. Monis (Author/Creator) - Australian Water Quality Centre
- Publication Details
- Advances in Parasitology Volume 78, Vol.78, pp.57-95
- Publisher
- Academic Press
- Identifiers
- 991005542892007891
- Copyright
- © 2012 Elsevier Ltd.
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Parasitology
- ESI research areas
- Microbiology