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Giardia duodenalis mouse model for the development of novel antigiardial agents
Journal article   Open access   Peer reviewed

Giardia duodenalis mouse model for the development of novel antigiardial agents

R.J. Abraham, M. O'Dea, B. Rusdi, S.W. Page, R. O'Handley and S. Abraham
Journal of Microbiological Methods, Vol.145, pp.7-9
2018
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Abstract

This study describes a neonatal mouse model of Giardia infection for development of novel antigiardials. Mice were infected with the axenically cultured Assemblage A BAH2c2 strain, with 105 trophozoites per animal recovered. This model proved to be robust and consistent for use in preliminary drug efficacy trials and drug development.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.246 Diarrheal Diseases
1.246.985 Cryptosporidium
Web Of Science research areas
Biochemical Research Methods
Microbiology
ESI research areas
Microbiology
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