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Journal article
Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015
Journal of the American College of Cardiology, Vol.70(1), pp.1-25
2017
PMCID: PMC5491406
PMID: 28527533
Abstract
Background
The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world.
Objectives
The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden.
Methods
CVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specific CVD deaths by a reference life expectancy. A sociodemographic index (SDI) was created for each location based on income per capita, educational attainment, and fertility.
Results
In 2015, there were an estimated 422.7 million cases of CVD (95% uncertainty interval: 415.53 to 427.87 million cases) and 17.92 million CVD deaths (95% uncertainty interval: 17.59 to 18.28 million CVD deaths). Declines in the age-standardized CVD death rate occurred between 1990 and 2015 in all high-income and some middle-income countries. Ischemic heart disease was the leading cause of CVD health lost globally, as well as in each world region, followed by stroke. As SDI increased beyond 0.25, the highest CVD mortality shifted from women to men. CVD mortality decreased sharply for both sexes in countries with an SDI >0.75.
Conclusions
CVDs remain a major cause of health loss for all regions of the world. Sociodemographic change over the past 25 years has been associated with dramatic declines in CVD in regions with very high SDI, but only a gradual decrease or no change in most regions. Future updates of the GBD study can be used to guide policymakers who are focused on reducing the overall burden of noncommunicable disease and achieving specific global health targets for CVD.
Details
- Title
- Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015
- Authors/Creators
- Gregory A. Roth - University of WashingtonCatherine Johnson - University of WashingtonAmanuel Abajobir - The University of QueenslandFoad Abd-Allah - Cairo UniversitySemaw Ferede Abera - Mekelle UniversityGebre Abyu - Mekelle UniversityMuktar Ahmed - Jimma UniversityBaran Aksut - Cleveland ClinicTahiya Alam - University of WashingtonKhurshid Alam - The University of MelbourneFrançois Alla - Université de LorraineNelson Alvis-Guzman - University of CartagenaStephen Amrock - Oregon Health & Science UniversityHossein Ansari - Zahedan University of Medical SciencesJohan Ärnlöv - Uppsala UniversityHamid Asayesh - Qom University of Medical Science and Health ServicesTesfay Mehari Atey - Mekelle UniversityLeticia Avila-Burgos - Instituto Nacional de Salud PúblicaAshish Awasthi - Sanjay Gandhi Post Graduate Institute of Medical SciencesAmitava Banerjee - University College LondonAleksandra Barac - University of BelgradeTill Bärnighausen - Harvard UniversityLars Barregard - University of GothenburgNeeraj Bedi - Jazan UniversityEzra Belay Ketema - Mekelle UniversityDerrick Bennett - University of OxfordGebremedhin Berhe - Mekelle UniversityZulfiqar Bhutta - Aga Khan UniversityShimelash Bitew - Wolaita Sodo UniversityJonathan Carapetis - The University of Western Australia, Perth, Western Australia, AustraliaJuan Jesus Carrero - Karolinska InstitutetDeborah Carvalho Malta - Universidade Federal de Minas GeraisCarlos Andres Castañeda-Orjuela - Instituto Nacional de Salud, Bogotá, ColombiaJacqueline Castillo-Rivas - Caja Costarricense de Seguro Social, San José, Costa RicaFerrán Catalá-López - University of València/INCLIVA Health Research Institute and CIBERSAM, València, SpainJee-Young Choi - Seoul National University HospitalHanne Christensen - Bispebjerg University Hospital, Copenhagen, DenmarkMassimo Cirillo - University of SalernoLeslie Cooper - Mayo Clinic, Rochester, MinnesotaMichael Criqui - University of California San DiegoDavid Cundiff - Long Beach, CaliforniaAlbertino Damasceno - Eduardo Mondlane UniversityLalit Dandona - University of Washington, SeattleRakhi Dandona - University of Washington, SeattleKairat Davletov - Institute of CardiologySamath Dharmaratne - University of PeradeniyaPrabhakaran Dorairaj - Centre for Chronic Disease ControlManisha Dubey - International Institute for Population SciencesRebecca Ehrenkranz - University of Washington, SeattleMaysaa El Sayed Zaki - Mansoura UniversityEmerito Jose A. Faraon - University of the Philippines ManilaAlireza Esteghamati - Tehran University of Medical SciencesTalha Farid - University of LouisvilleMaryam Farvid - Harvard UniversityValery Feigin - Auckland University of TechnologyEric L. Ding - Harvard UniversityGerry Fowkes - University of Edinburgh, Edinburgh United KingdomTsegaye Gebrehiwot - Jimma UniversityRichard Gillum - Harvard UniversityAudra Gold - University of Washington, SeattlePhilimon Gona - University of Massachusetts BostonRajeev Gupta - Eternal Heart Care Center and Research Institute, Jaipur, IndiaTesfa Dejenie Habtewold - University of GroningenNima Hafezi-Nejad - Tehran University of Medical SciencesTesfaye Hailu - Mekelle UniversityGessessew Bugssa Hailu - Mekelle UniversityGraeme Hankey - The University of Western Australia, Perth, Western Australia, AustraliaHamid Yimam Hassen - Mizan Tepi UniversityKalkidan Hassen Abate - Jimma UniversityRasmus Havmoeller - Karolinska InstitutetSimon I. Hay - University of Washington, SeattleMasako Horino - Nevada Division of Public and Behavioral HealthPeter J. Hotez - Baylor College of MedicineKathryn Jacobsen - George Mason UniversitySpencer James - Denver Health/University of Colorado, Denver, ColoradoMehdi Javanbakht - University of Aberdeen, Aberdeen, United KingdomPanniyammakal Jeemon - Centre for Chronic Disease ControlDenny John - University of WashingtonJost Jonas - Heidelberg (Poland)Yogeshwar Kalkonde - Society for Education, Action and Research in Community Health, Gadchiroli, IndiaChante Karimkhani - University Hospitals of ClevelandAmir Kasaeian - Tehran University of Medical SciencesYousef Khader - Jordan University of Science and TechnologyAbdur Khan - University of LouisvilleYoung-Ho Khang - Seoul National UniversitySahil Khera - New York Medical College, Valhalla, New YorkAbdullah T. Khoja - Imam Mohammad ibn Saud Islamic UniversityJagdish Khubchandani - Ball State UniversityDaniel Kim - Northeastern UniversityDhaval Kolte - Brown UniversitySoewarta Kosen - Health Policy and Humanities, National Institute of Health Research and Development, Jakarta, IndonesiaKristopher J. Krohn - University of Washington, SeattleG. Anil Kumar - Public Health Foundation of IndiaGene F. Kwan - Boston University School of MedicineDharmesh Kumar Lal - Public Health Foundation of IndiaAnders Larsson - Uppsala UniversityShai Linn - University of HaifaAlan Lopez - The University of MelbournePaulo A. Lotufo - University of Sao PauloHassan Magdy Abd El Razek - Mansoura UniversityReza Malekzadeh - Tehran University of Medical SciencesMohsen Mazidi - Chinese Academy of Sciences, Beijing, ChinaToni Meier - Martin Luther University Halle-WittenbergKidanu Gebremariam Meles - Mekelle UniversityGeorge Mensah - National Institutes of HealthAtte Meretoja - The University of MelbourneHaftay Mezgebe - Mekelle UniversityTed Miller - Pacific Institute for Research & Evaluation, Beltsville, MarylandErkin Mirrakhimov - Kyrgyz State Medical AcademyShafiu Mohammed - Ahmadu Bello UniversityAndrew E. Moran - Columbia UniversityKamarul Imran Musa - University of Science Malaysia, Penang, MalaysiaJagat Narula - The Mount Sinai Hospital, New York, New YorkBruce Neal - The George Institute for Global Health, Newtown, New South Wales, AustraliaFrida Ngalesoni - Ministry of Health and Social Welfare, Dar es Salaam, TanzaniaGrant Nguyen - University of Washington, SeattleCarla Makhlouf Obermeyer - American University of BeirutMayowa Owolabi - University of IbadanGeorge Patton - The University of MelbourneJoão Pedro - Universidade do PortoDima Qato - University of Illinois ChicagoMostafa Qorbani - Alborz University of Medical Sciences, Karaj, IranKazem Rahimi - University of OxfordRajesh Kumar Rai - Society for Health and Demographic Surveillance, Birbhum, IndiaSalman Rawaf - Imperial College LondonAntônio Ribeiro - Universidade Federal de Minas GeraisSaeid Safiri - Maragheh University of Medical Sciences, Maragheh, IranJoshua A. Salomon - Harvard UniversityItamar Santos - University of Sao PauloMilena Santric Milicevic - University of BelgradeBenn Sartorius - University of KwaZulu-Natal, Durban, South AfricaAletta Schutte - North-West University, Potchefstroom, South AfricaSadaf Sepanlou - Tehran University of Medical SciencesMasood Ali Shaikh - Independent Consultant, Islamabad, PakistanMin-Jeong Shin - University of SeoulMehdi Shishehbor - Cleveland ClinicHirbo Shore - Haramaya UniversityDiego Augusto Santos Silva - Universidade Federal de Santa CatarinaEugene Sobngwi - University of Yaoundé, Yaoundé, CameroonSaverio Stranges - Luxembourg Institute of HealthSoumya Swaminathan - Indian Council of Medical Research, New Delhi, IndiaRafael Tabarés-Seisdedos - University of València/INCLIVA Health Research Institute and CIBERSAM, València, SpainNiguse Tadele Atnafu - Mizan Tepi UniversityFisaha Tesfay - Mekelle UniversityJ.S. Thakur - Postgraduate Institute of Medical Education and ResearchAmanda Thrift - Monash UniversityRoman Topor-Madry - Jagiellonian UniversityThomas Truelsen - University of CopenhagenStefanos Tyrovolas - Universitat de BarcelonaKingsley Nnanna Ukwaja - Federal Teaching Hospital AbakalikiOlalekan Uthman - University of WarwickTommi Vasankari - UKK InstituteVasiliy Vlassov - National Research University Higher School of Economics, Moscow, RussiaStein Emil Vollset - Norwegian Institute of Public HealthTolassa Wakayo - Jimma UniversityDavid Watkins - University of Washington, SeattleRobert Weintraub - Royal Children’s Hospital, Melbourne, Victoria, AustraliaAndrea Werdecker - Federal Institute for Population ResearchRonny Westerman - Federal Institute for Population ResearchCharles Shey Wiysonge - Cochrane South Africa, Tygerberg, South AfricaCharles Wolfe - King's College LondonAbdulhalik Workicho - Jimma UniversityGelin Xu - Nanjing UniversityYuichiro Yano - Northwestern UniversityPaul Yip - University of Hong KongNaohiro Yonemoto - Kyoto UniversityMustafa Younis - Jackson State UniversityChuanhua Yu - Wuhan UniversityTheo Vos - University of Washington, SeattleMohsen Naghavi - University of Washington, SeattleChristopher Murray - University of Washington, SeattleInstitutionen för medicin, avdelningen för samhällsmedicin och folkhälsa
- Publication Details
- Journal of the American College of Cardiology, Vol.70(1), pp.1-25
- Publisher
- Elsevier Inc
- Identifiers
- 991005591501507891
- Copyright
- © 2017 The Authors
- Murdoch Affiliation
- Centre for Healthy Ageing
- Language
- English
- Resource Type
- Journal article
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