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Granulomatous meningoence-phalomyelitis in 21 dogs
Journal article   Peer reviewed

Granulomatous meningoence-phalomyelitis in 21 dogs

J.B. Thomas and C.E. Eger
Journal of Small Animal Practice, Vol.30(5), pp.287-293
1989
DOI: https://doi.org/10.1111/j.1748-5827.1989.tb01558.x
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Abstract

Granulomatous meningoencephalomyelitis (GME) is a well recognised disease entity affecting dogs. It manifests in a wide variety of clinical syndromes. The lesion is characterised by focal or disseminated non‐caseating granulomas in the brain and spinal cord, non‐suppurative meningitis and marked perivascular lymphoid cuffing. The clinical signs can be acute and rapidly progressive or can manifest as a chronic relapsing disease. In this survey, 12 clinical cases were referred to Murdoch University Veterinary Hospital and nine cases were submitted for necropsy. While cerebrospinal fluid examination in seven of these cases suggested inflammatory disease, necropsy confirmed the presence of GME. An immunohistochemical technique for detection of distemper virus antigen failed to identify the presence of distemper virus antigen in any of the cases. It was concluded that distemper virus was not involved in the aetiology of these 21 cases all of which were confirmed by post mortem examination.

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Source: InCites

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Citation topics
3 Agriculture, Environment & Ecology
3.232 Veterinary Sciences
3.232.1120 Veterinary Oncology
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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