Journal article
Gut microbiota fermentation profiles of pre-digested mycoprotein (Quorn) using faecal batch cultures in vitro: a preliminary study
International journal of food sciences and nutrition, Vol.74(3), pp.327-337
2023
PMID: 37221881
Abstract
High-fibre diets are beneficial for many health outcomes via a wide range of mechanisms including gut microbiota fermentation-derived short-chain fatty acid (SCFAs) production. Mycoprotein (marketed as Quorn) is a food high in fibre (>6 g/100 g wet weight (ww)) and protein (13 g/100 g ww) which has been shown to have positive effects on glycemic control and appetite in humans. Nevertheless, the mechanisms underpinning this are poorly understood. Here, we investigate the changes in gut microbiota α- and β-diversity, pH and SCFAs production in faecal batch cultures supplemented with pre-digested mycoprotein (Quorn), soy, chicken and control (unsupplemented) using eight fresh stools from healthy donors. The results showed that pre-digested mycoprotein did not alter pH (p = .896), α- or β-diversity of the gut microbiota when compared to the control, soy, and chicken. Nevertheless, chicken led to a significant increase in total SCFAs post-24 h vs. control (+57.07 mmol/L, p = .01). In particular, propionate increased when compared to soy (+19.59 mmol/L, p = .03) and the control (+23.19 mmol/L, p < .01). No other differences in SCFAs were detected. In conclusion, pre-digested mycoprotein was not fermented in vitro by healthy gut microbiota in the settings of this experiment.
Details
- Title
- Gut microbiota fermentation profiles of pre-digested mycoprotein (Quorn) using faecal batch cultures in vitro: a preliminary study
- Authors/Creators
- Anna Cherta-Murillo - Imperial College LondonNathan P. Danckert - St Mary's HospitalMaria Valdivia-Garcia - Hammersmith HospitalEdward S. Chambers - Imperial College LondonLauren Roberts - Imperial College LondonJesus Miguens-Blanco - Imperial College LondonJulie A.K. McDonald - Imperial College LondonJulien R. Marchesi - St Mary's HospitalGary S. Frost - Hammersmith Hospital
- Publication Details
- International journal of food sciences and nutrition, Vol.74(3), pp.327-337
- Number of pages
- 11
- Grant note
- Biotechnology and Biological Sciences Research Council (http://data.elsevier.com/vocabulary/SciValFunders/501100000268) National Institute for Health and Care Research (http://data.elsevier.com/vocabulary/SciValFunders/501100000272) Medical Research Council (http://data.elsevier.com/vocabulary/SciValFunders/501100000265) Quorn Foods Ltd. Quorn Foods Ltd HEALTH-2009-241592 EuroCHIP / Seventh Framework Programme (http://data.elsevier.com/vocabulary/SciValFunders/100011102) Imperial College’s NIHR
- Identifiers
- 991005884954007891
- Copyright
- © 2023 the author(s).
- Murdoch Affiliation
- Centre for Computational and Systems Medicine
- Language
- English
- Resource Type
- Journal article
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