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HLA-A, -B, -C, -DRB1, DRB3, DRB4, DRB5 and DQB1 polymorphism detected by PCR-SSP in a semi-urban HIV-positive Ugandan population
Journal article   Peer reviewed

HLA-A, -B, -C, -DRB1, DRB3, DRB4, DRB5 and DQB1 polymorphism detected by PCR-SSP in a semi-urban HIV-positive Ugandan population

P. Krausa, S. McAdam, M. Bunce, J. Whitworth, B. Biryahwaho, N. French, B. Tugume, C. Gilks and F. Gotch
Experimental and Clinical Immunogenetics, Vol.16(1), pp.17-25
1999
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Abstract

PCR-SSP was used to HLA-type a cohort of Ugandan HIV-positive individuals. The results represent a more comprehensive description of HLA in an African population than previously described and are in concordance with data from a general Black population. Substantial differences exist between this population and Caucasoid populations in which immunological responses to HIV have been investigated; this emphasises that the main HLA-restrictive elements for HIV-specific cytotoxic T lymphocytes will most likely be different for each population.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.6 Immunology
1.6.607 MHC Diversity
Web Of Science research areas
Biochemistry & Molecular Biology
Genetics & Heredity
Immunology
ESI research areas
Molecular Biology & Genetics
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